Research Journal of Pharmacognosy and Phytochemistry

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0975-4385 (Online)
0975-2331 (Print)


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Hedychium spicatum: Evaluation of Its Nootropic Effect in Mice

Author(s): R. V. Shete, S.L. Bodhankar

Email(s): rvshete09@gmail.com

DOI: Not Available

Address: R. V. Shete1 and S.L. Bodhankar2
1Rajgad Dyanpeeth’s College of Pharmacy, Bhor, Dist. Pune-412206
2Department of Pharmacology, Bharati Vidyapeeth University, Poona College of Pharmacy, Pune- 411038
*Corresponding Author

Published In:   Volume - 2,      Issue - 5,     Year - 2010

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ABSTRACT:
Alzheimer disease is a neurodegenerative disorder characterized by a progressive loss of memory and cognition. To improve memory nootropic agents like donepezil, piracetam are generally used. Due to side effects of such drugs their uses are limited. Hedychium spicatum commonly known as Kapurkachri, is traditionally claimed and being used in Indian subcontinent for its nootropic potential. In the present work H. spicatum was investigated for its pharmacological effect on central nervous system. The elevated plus maze and double unit mirrored chamber test were employed to assess the nootropic potential of n-butanol fraction (3, 10 and 30 mg/kg) in mice. Preliminary phytochemical screening along with HPTLC studies confirmed the presence of saponin. Hence, H. spicatum might prove to be a useful as a memory restorative agent in the treatment of dementia seen in the Alzheimer’s disease.


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Cite this article:
R. V. Shete, S.L. Bodhankar. Hedychium spicatum: Evaluation of Its Nootropic Effect in Mice. Research J. Pharmacognosy and Phytochemistry 2010; 2(5): 403-406.

Cite(Electronic):
R. V. Shete, S.L. Bodhankar. Hedychium spicatum: Evaluation of Its Nootropic Effect in Mice. Research J. Pharmacognosy and Phytochemistry 2010; 2(5): 403-406.   Available on: https://rjpponline.org/AbstractView.aspx?PID=2010-2-5-14


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Research Journal of Pharmacognosy and Phytochemistry (RJPP) is an international, peer-reviewed journal, devoted to pharmacognosy...... Read more >>>

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DOI: 10.5958/0975-4385 

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Research Journal of Pharmacognosy and Phytochemistry (RJPP) (ISSN: print-0975-2331, Online-0975-4385) is an international, peer-reviewed journal, devoted to pharmacognosy. The aim of RJPP is to increase the impact of pharmacognostic research both in academia and industry, with strong emphasis on quality and originality. RJPP publishes Original Research Articles, Short Communications, Review Articles in all areas of Pharmacognosy and Phytochemistry.

The journal is published quaterly every year in last week of March, June, September and December.    
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