ABSTRACT:
Worldwide obesity has increased dramatically coupled with metabolic syndrome (MetS), which is defined by central obesity, insulin resistance, dyslipidemia, hypertension, and elevated fasting glucose. It dramatically raises the risk of cardiovascular disease, atherosclerosis, and type 2 diabetes. The International Diabetes Federation (IDF) states that any two abnormalities—elevated fasting glucose, high triglycerides, poor HDL cholesterol, or high blood pressure—must be present in addition to central obesity for a diagnosis. Conventional therapies including statins, thiazolidinediones, GLP-1 agonists, and DPP-4 inhibitors may have adverse effects and be difficult to get, despite the NCEP-ATP III recommendations' emphasis on regulating glucose and cholesterol levels. Herbal medicines are become more popular as supplementary treatments. Herbal treatments successfully reduced blood glucose, triglycerides, blood pressure, and waist circumference while raising HDL cholesterol, according to a comprehensive assessment of 12 randomized controlled studies. Their advantages come from controlling lipid metabolism, improving insulin sensitivity, and lowering inflammation. Herbal remedies provide a promising, cost-effective supplementary method, but lifestyle adjustment is still crucial. To verify long-term safety, larger clinical trials are required.