Author(s): Shital Kalekar, Payal Ambhore, Nidhi Vichare, Ganesh More

Email(s): kalekar15shital@gmail.com , payalambhore02@gmail.com , nidhivichare523@gmail.com , ganesh.more@dypatiluniversitypune.edu.in

DOI: 10.52711/0975-4385.2026.00002   

Address: Shital Kalekar, Payal Ambhore, Nidhi Vichare, Ganesh More
DY Patil University, Ambi, Pune.
*Corresponding Author

Published In:   Volume - 18,      Issue - 1,     Year - 2026


ABSTRACT:
The present study involves the formulation and evaluation of a topical herbal cream incorporating Spathodea campanulata (African tulip tree) flower extract. Spathodea campanulata, native to tropical Africa, is widely recognized in traditional medicine for its therapeutic properties, particularly in the treatment of wounds, inflammation, and microbial infections. The vibrant orange-red flowers of the plant are known to be rich in bioactive phytochemicals such as flavonoids, tannins, saponins, and phenolic compounds, which contribute to their antioxidant, anti-inflammatory, and antimicrobial effects. Fresh flowers were collected and subjected to Soxhlet extraction using ethanol to obtain a concentrated extract. The extract was then incorporated into a cream base composed of paraffin, beeswax, borax, methylparaben, and rose oil. The formulated cream was evaluated for key physicochemical characteristics such as pH, spreadability, viscosity, homogeneity, and stability. Organoleptic evaluation confirmed the product's acceptable color, texture, and odour. The cream showed suitable consistency for topical application and did not cause any irritation during the skin irritancy test. Antimicrobial activity was assessed using the agar well diffusion method against selected bacterial strains. The extract demonstrated dose-dependent inhibitory activity, particularly against Gram-positive bacteria. These findings are consistent with the traditional use of Spathodea campanulata in managing skin infections and promoting wound healing. In conclusion, the formulated herbal cream exhibited good physical stability, safety, and antimicrobial potential. The study highlights the therapeutic value of Spathodea campanulata flowers and supports their incorporation into natural, skin-friendly topical formulations.


Cite this article:
Shital Kalekar, Payal Ambhore, Nidhi Vichare, Ganesh More. Formulation and Evaluation of Herbal cream using Spathodea campanulata. Research Journal of Pharmacognosy and Phytochemistry. 2026; 18(1):5-2. doi: 10.52711/0975-4385.2026.00002

Cite(Electronic):
Shital Kalekar, Payal Ambhore, Nidhi Vichare, Ganesh More. Formulation and Evaluation of Herbal cream using Spathodea campanulata. Research Journal of Pharmacognosy and Phytochemistry. 2026; 18(1):5-2. doi: 10.52711/0975-4385.2026.00002   Available on: https://rjpponline.org/AbstractView.aspx?PID=2026-18-1-2


REFERENCES:
1.    Kaur L, Singh A, Singh A, Kaur T. A review on herbal cosmetics. Int J Pharm Drug Anal. 2021; 9(3):196-200.
2.    Fatima A, Shafi M, Fatima G, Ahmed I, Mohsin M. Phytochemistry and pharmacological review: Spathodea campanulata. Indian J Pharm Biol Res. 2021; 9(2): 1-6.
3.    Ofori-Kwakye K, Kwapong AA, Adu F. Antimicrobial activity of extracts and topical products of the stem bark of Spathodea campanulata for wound healing. Afr J Tradit Complement Altern Med. 2009 Mar 7; 6(2):168-74. doi:10.4314/ajtcam. v6i2.57089.
4.    Cristani M, Micale N. Bioactive compounds from medicinal plants as potential adjuvants in the treatment of mild acne vulgaris. Molecules. 2024 May 19; 29(10): 2394. doi:10.3390/molecules29102394.
5.    Dhyani A, Singh N, Nautiyal V. Formulation and evaluation of multipurpose herbal cream. J Drug Deliv Ther. 2019; 9(2): 341-3.
6.    Badwaik C, Lade U, Agarwal T, Barsagade P, Nandgave M. Formulation and evaluation of herbal face cream. Int J Pharm Res Appl. 2022 Jan-Feb; 7(1): 955-60.
7.    Azwanida NN. A review on the extraction methods use in medicinal plants, principle, strength and limitation. Med Aromat Plants. 2015; 4:196. doi:10.4172/2167-0412.1000196.
8.    Nair SS, Mathew M, Sreena K. Formulation and evaluation of herbal cream containing Curcuma longa. Int J Pharm Chem Sci. 2012 ec; 1(4):1-6.
9.    Barel AO, Paye M, Maibach HI, editors. Handbook of cosmetic science and technology. 4th ed. Boca Raton (FL): CRC Press; 2014. doi:10.1201/b16716.
10.    Kaur LP, Guleri TK. Topical gel: a recent approach for novel drug delivery. Asian J Biomed Pharm Sci. 2013; 3(17).
11.    Jani R, Jani K, Mallikarjuna SC, Patel D. Preparation and evaluation of topical gel Valdecoxib. Int J Pharm Sci Res. 2010; 2(1): 51-4.
12.    Priyadarsini S, Kumar PR, Margesan MT. Formulation and evaluation of a herbal antibacterial cream from ethyl acetate extract of leaves of Spinacia oleracea Linn. against Aeromonas skin and soft tissue infections. Int J Green Pharm. 2018; 12: S537-S42.
13.    Bauer AW, Kirby WMM, Sherris JC, Turck M. Antibiotic susceptibility testing by a standardized single disk method. Am J Clin Pathol. 1966; 45: 493-6.
14.    Gul R, Jan SU, Faridullah S, Sherani S, Jahan N. Preliminary phytochemical screening, quantitative analysis of alkaloids, and antioxidant activity of crude plant extracts from selected regions of Pakistan. BMC Chem. 2017; 11: 54.
15.    Blois MS. Antioxidant determinations by the use of a stable free radical. Nature. 1958; 181:1199-200. doi:10.1038/1811199a0.





Recomonded Articles:

Author(s): Anshuman Singh, Bhupendra Vyas

DOI: 10.5958/0975-4385.2018.00052.3         Access: Open Access Read More

Author(s): Baviskar H. P., Dhake G. T., Kasai M. A., Chaudhari N. B., Deshmukh T. A.

DOI: 10.5958/0975-4385.2017.00024.3         Access: Open Access Read More

Author(s): Kavitha M, Vadivu R, Radha R

DOI: 10.5958/0975-4385.2015.00037.0         Access: Open Access Read More

Author(s): Punita R. Maurya, Swati R. Dhande, Yadunath M. Joshi, Vilasrao J. Kadam

DOI:         Access: Open Access Read More

Author(s): S C Baviya, R Radha, N Jayshree

DOI: 10.5958/0975-4385.2015.00038.2         Access: Open Access Read More

Author(s): Chandrakant P. Rathod, Mahavir H. Ghante

DOI: 10.52711/0975-4385.2021.00022         Access: Open Access Read More

Author(s): Raje VN, Yadav AV, Shelar PA

DOI:         Access: Open Access Read More

Author(s): Kalpana Patil, Swati Dhande, Vilasrao Kadam

DOI:         Access: Open Access Read More

Author(s): Obidoa, Onyechi, Joshua, Parker Elijah, Egemole, John C., Ikeyi Adachukwu

DOI:         Access: Open Access Read More

Author(s): Praveen S Nayak, Shweta Nayak, Ranjan Shety, P Das

DOI:         Access: Open Access Read More

Author(s): Vidula Salvi, Yadunath Joshi, Swati Dhande , Vilasrao Kadam

DOI:         Access: Open Access Read More

Author(s): AK Meena, Uttam S Niranjan, AK Yadav, Brijendra Singh, AK Nagaria, A Gaurav, MM Rao

DOI:         Access: Open Access Read More

Author(s): Mohd Asif, Mohd Wasim Ahmed, Shahidul Khair, Murugeswaran R, Rampratap Meena, Mokhtar Alam, Shoeb Ahmed Ansari, Mohd Tariq, Rakesh Kumar Negi

DOI: 10.5958/0975-4385.2019.00035.9         Access: Open Access Read More

Author(s): Puneet Kumar Rai, Dev Raj Sharma, Amit Sharma

DOI: 10.5958/0975-4385.2015.00029.1         Access: Open Access Read More

Author(s): K Amutha , D Victor Arokia Doss

DOI:         Access: Open Access Read More

Author(s): Kirteebala P Pawar, Milind J Bhitre, Priyanka V Kalamkar, Mohan K Kale

DOI: 10.5958/0975-4385.2015.00013.8         Access: Open Access Read More

Author(s): K Mekala, R Radha

DOI: 10.5958/0975-4385.2015.00035.7         Access: Open Access Read More

Author(s): Anjali M. Wankhade, Poonam C. Rahangdale

DOI: 10.52711/0975-4385.2023.00037         Access: Open Access Read More

Author(s): Mamta Tiwari, Pushpraj S. Gupta, Nisha Sharma

DOI: 10.5958/0975-4385.2018.00014.6         Access: Open Access Read More


Recent Articles




Tags