Acidity is a medical condition caused by an excess of acid production. This acid is produced by the stomach glands. Acidity causes symptoms such as stomach ulcers, gastric inflammation, heartburn, and dyspepsia. Acidity is a global issue caused by an imbalance between the acid-secreting mechanisms of the stomach and the proximal intestine. It causes a lot of problems in the lives of many people. An antacid reduces acidity and provides relief. This review article discusses different polyherbal formulations (PHF) used to treat gastric acidity. Due to its role in medicine and therapy, PHF has been used all over the world. The current study discusses a variety of commercial and non-commercial polyherbal formulations used worldwide to treat gastric acidity, as well as their therapeutic potential, clinical and preclinical outcomes, and safety and efficacy. This review will make it easier to learn everything about the previous scientific research as well as the crucial details about the antacid properties of polyherbal preparations, which will encourage young researchers to conduct additional studies in the future to protect people from gastric acidity. Natural herbs and their extracts are used in herbal treatment as an alternative to conventional medication to treat various conditions. It has been demonstrated that several medications contain medicinal components useful for treating ulcers or stomach acidity. The subject of the current work is the claim that a polyherbal formulation can be utilised as an alternative to currently available antacid formulations on the market. As a result, those plants that can reduce stomach acid are chosen, and a formulation is created.
Cite this article:
Prerana Musale, S. D. Mankar. A Review on Polyherbal Formulation Used in the Treatment of Gastric Acidity. Research Journal of Pharmacognosy and Phytochemistry. 2023; 15(2):173-8. doi: 10.52711/0975-4385.2023.00027
Prerana Musale, S. D. Mankar. A Review on Polyherbal Formulation Used in the Treatment of Gastric Acidity. Research Journal of Pharmacognosy and Phytochemistry. 2023; 15(2):173-8. doi: 10.52711/0975-4385.2023.00027 Available on: https://rjpponline.org/AbstractView.aspx?PID=2023-15-2-13
1. Sharma S, Sharma P, Katiyar D, Goel R, Sahoo J. Formulation, standardization and screening of polyherbal churna for antacid activity. Int. J. Res. Ayurveda Pharm. 2018;9(4):94-97
2. Pawar SS, Pande VV, Girme A and Sanklecha VM. Biological Standardization of Some Herbal Formulations for Antacid Activity. Austin Pharmacol Pharm. 2018; 3(1): 1015.
3. Dinbandhu J, Yogita J, Sapna M, Anil K. Preparation and biological standardization of antacid formulation. WJPR. 2017 Sep 29;6(15):716-21.
6. Mishra E, Shetty N, Waghmare M. Antacid: An Overview. Int J Recent Sci Res. 2021;12(04):41448-41453
7. Houshia OJ, AbuEid M, Zaid O, Zaid M, Al-daqqa N. Assessment of the value of the antacid contents of selected palestinian plants. American Journal of Chemistry. 2012;2(6):322-5.
8. Gadhve MV, Garje VN, Narad VR., Gaikwad DD and Jadhav S.J. Formulation Development and Evaluation of Rapidly Disintegrating Antacid Tablets. Int J Recent Sci Res. 2016;7(10):13802-13806
9. Tyler VE. Phytomedicines: back to the future. Journal of Natural Products. 1999 Nov 29;62(11):1589-92.
10. Pegu KD. Pharmacology of antacids. Southern African Journal of Anaesthesia and Analgesia. 2020 Nov 13;26(6):S133-136.
11. Pal SK, Shukla Y. Herbal medicine: current status and the future. Asian pacific journal of cancer prevention. 2003 Aug 20;4(4):281-8.
12. Salisbury BH, Terrell JM. Antacids. In: StatPearls. Treasure Island (FL): StatPearls Publishing; August 15, 2022.
13. Milner A. Applied pharmacology in anaesthesiology and critical care. Medpharm Publications Pty Limited; 2012. 406-11
14. Maradey-Romero C, Fass R. New and future drug development for gastroesophageal reflux disease. Journal of Neurogastroenterology and Motility. 2014 Jan;20(1):6.
15. Venables TL, Newland RD, Patel AC, Hole J, Wilcock C, Turbitt ML. Omeprazole 10 milligrams once daily, omeprazole 20 milligrams once daily, or ranitidine 150 milligrams twice daily, evaluated as initial therapy for the relief of symptoms of gastro-oesophageal reflux disease in general practice. Scandinavian journal of gastroenterology. 1997 Jan 1;32(10):965-73.
16. Prinz CH, Kajimura MA, Scott D, Helander HE, Shin JA, Besancon MA, Bamberg KR, Hersey S, Sachs G. Acid secretion and the H, K ATPase of stomach. The Yale journal of biology and medicine. 1992 Nov;65(6):577.
17. Reddy MS, Reddy DR, Prasad NA, inventors; Reddy, Malireddy S., Damavarapu Radha Krishna, Prasad, Naraparaju AV, assignee. Herbal and pharmaceutical drugs enhanced with probiotics. United States patent US 6,080,401. 2000 Jun 27.
18. Kaderkar Dattatray Shrikar1 , Tamboli Ashpak M. Review on Concept and Scope of Polyherbal FormulationJune 2020 | IJIRT | Volume 7 Issue 1 | ISSN: 2349-6002
19. Kumar S, Dobos GJ, Rampp T. The Significance of Ayurvedic Medicinal Plants. J Evid Based Complementary Altern Med, 2017; 22(3): 494-501.
20. Khan, wasim raza ali, et al. opportunities and challenges to develop polyherbal formulations in india-a swot study. 2022;11(10):737-753.
21. karole S, Shrivastava S, Thomas S, Soni B, Khan S, Dubey J, Dubey SP, Khan N, Jain DK, Polyherbal Formulation Concept for Synergic Action: A Review, Journal of Drug Delivery and Therapeutics. 2019; 9(1-s):453-466
22. Che CT, Wang ZJ, Chow MS, Lam CW. Herb-herb combination for therapeutic enhancement and advancement: theory, practice and future perspectives. Molecules. 2013 May 3;18(5):5125-41.
23. Khare B, Shukla TP. A Review on Polyherbal Formulation Used IN The Treatment of Rheumatoid Arthritis. Journal of Advanced Scientific Research. 2022 Feb 28;13(01):31-42.
24. Parasuraman S, Thing GS, Dhanaraj SA. Polyherbal formulation: Concept of ayurveda. Pharmacognosy reviews. 2014 Jul;8(16):73.
26. Spinella M. The importance of pharmacological synergy in psychoactive herbal medicines. Alternative Medicine Review. 2002 Apr 1;7(2):130-7.
27. Suryakumari Chalakanti et al. Formulation and evaluation of polyherbal drugs powder by using antacid and anti-ulcer treatment. International Journal of Applied Research 2021; 7(1): 235-241
28. Mazumder J, Pathak D, Kumria R. Antacid studies of Newly Developed Poly Herbal Formulation. International Journal of Drug Delivery Technology. 2016;6(1):27-9.
29. Joydeep Mazumder1*, Devender Pathak1, Rachna Kumria. Antacid Studies of Newly Developed Polyherbal Formulation. International Journal of Drug Delivery Technology 2016; 6(1); 27-29
30. Roopa G, Bhat RS, Dakshina MS. Formulation and evaluation of an antacid and anti-ulcer suspension containing herbal drugs. Biomedical and Pharmacology Journal. 2015 Mar 25;3(1):01-6.
31. Aswathan HN, Kaushik u, Lachake P, Shreedhara cs. Pharmacognosy research 2009 JUL-Aug;1(4):224