Mohini B. Shelke, Dattaprasad N. Vikhe, Ravindra S. Jadhav
Mohini B. Shelke*, Dattaprasad N. Vikhe, Ravindra S. Jadhav
Department of Pharmacognosy, Pravara Rural College of Pharmacy, Pravaranagar A/p. Loni - 413736, Tal - Rahata, Dist.- Ahmednagar (M.S.)
Volume - 14,
Issue - 3,
Year - 2022
With an adding number of people seeking remedies and health approaches free of synthetic chemicals' side goods, medicinal sauces are moving from the borderline to the mainstream. Over 3000 medicinal shops are officially recognized in India. In India, it is believed that over 6000 businesses sell traditional, folk, and herbal medicines. This composition aims to give a comprehensive review on the phytochemical and pharmacological aspects of Caralluma fimbriata. It's attained from timbers throughout lesser corridor of India, it's extensively used in traditional medicinal system of India has been reported to retainanti-obesity, antioxidant, and anticancer exertion. It's known as a rich source of tannins, flavonoids, phenols, glycosides. Traditional drug uses the Caralluma rubric. The current composition covered the taxonomy of Caralluma into subgenera, the number of species, their distribution in different corridor of the world, and the pharmacological conduct of distinct Caralluma species. The antifungal and anthelmintic exertion of ethyl acetate and n-butanol excerpts from the stem of Caralluma fimbriata through, ascendens, a member of the Asclepiadaceae family, was delved in this work. Antifungal and anthelmintic parcels were delved against Aspergillusniger and Candida albicans, as well as earthworms Pheritima posthuma. It's discovered in India and is used as a carminative, anthelmintic, anti-diabetic, ant hyperglycemic, appetite suppressant, and other traditional drugs. Caralluma adscendens var. adscendens and Caralluma adscendens var. fimbriata are two comestible species plant in Maharashtra.
Cite this article:
Mohini B. Shelke, Dattaprasad N. Vikhe, Ravindra S. Jadhav. A Review on Caralluma adscendens: A Potential Medicinal Herb. Research Journal of Pharmacognosy and Phytochemistry. 2022; 14(3):219-4. doi: 10.52711/0975-4385.2022.00039
Mohini B. Shelke, Dattaprasad N. Vikhe, Ravindra S. Jadhav. A Review on Caralluma adscendens: A Potential Medicinal Herb. Research Journal of Pharmacognosy and Phytochemistry. 2022; 14(3):219-4. doi: 10.52711/0975-4385.2022.00039 Available on: https://rjpponline.org/AbstractView.aspx?PID=2022-14-3-13
1. A. D. Russel and J. R. Furr, J. Appl. Bacteriol., 43, 253 (1977).
2. Al-Harbi, M.M., S. Qureshi, M. Raza, M.M. Ahmed, M. Afzal and S.A.H. Shah. Evaluation of Caralluma tuberculafapretreatment for the protection of rat gastric mucosa against toxic damage.Toxicol.Appl. Pharm 1994; 128: 1-8.
3. Anon P, Opabode JI and Adegboye OC. Application of biotechnology for the improvement of nigerian indigenous leafy vegetables. Africa J Biotech.;4(3): 138-142. (2005).
4. Anonymous, Wealth of India, Edn 2, (5), C.S.I.R., New Delhi; 1985. p. 27-29.
5. Archana R. Pawar*, Prof. Dattaprasad N. Vikhe, Dr. R. S. Jadhav. "Recent Advances in Extraction Techniques of Herbals – A Review". Asian Journal of Research in Pharmaceutical Sciences. 10(4): October - December, 2020. Page no. 287-292.
6. Bader A, Braca A, De Tommasi N, Morelli I (2003). Further constituents from Caralluma negevensis. Phytochemistry. 62:1277-1281.
7. Bingtao Li, Michael G, Douglas SW. Asclepiadaceae. In Flora of China. Published by Science Press (Beijing) and Missouri Botanical Garden Press. Vol.16. P.189.] [S.I. Ali. Caralluma. In Flora of Pakistan. Published by Science Press (Beijing) and Missouri Botanical Garden Press. p.46.
8. Borget, M. Spices plants. In: R. Coste (ed.), The tropical Agriculturist, Macmillan, London, p 114. (1993).
9. Deepak Prashar and Sanjay Saklani. "Pharmaceutical and Economical Aspects of Medicinal Herbs: An Overview". Research J. Pharmacognosy and Phytochemistry 2011; 3(5):187-190. Wungsem Rungsung, Sreya Dutta, Jayram Hazra. "Pharmacognostical Approach towards Authentication and Quality Evaluation of Medicinal Plants-A Compendious Description". Research J. Pharmacognosy and Phytochemistry 2013; 5(2): 77-83.
10. Deepak, D, S. Srivastav and A. Khare.Progress in the Chemistry of Organic Natural Products.Springerlink 1997; 71: 169-325.
11. Delazar A, Nahar L, Hamedeyazdan S, Sarker SD. Microwaveassisted extraction in natural products isolation. Methods Mol Biol. 2012; 864:89-115.
12. Donald P. Briskin, Plant Physiology, 2000, Vol. 124, pp. 507–51426) Jadge DR, Naik JB (2009). Anti-inflammatory Activity of Ethanolic and Aqueous Extracts of Carallumaadscendens. Journal of Pharmacy Research 2(7):1228-1229.
13. Egon Stahl. Thin Layer Chromatography, A Laboratory Handbook II (ed) Springer International Edition, Toppan Company Ltd. 1969; Tokyo, Japan.
14. F. Kavanagah, Analytical Microbiology, Vol. II, Academic Press, New York (1972).
15. F. Rohner-Jeanrenaud and B. Jeanrenaud, “Obesity, leptin, and the brain,” New England Journal of Medicine, vol. 334, no. 5, pp. 324–325, 1996.
16. FAO. Fruit and Vegetable for health. Report of a joint FAO/WHO workshop. 2005.
17. G. W. Thorn, R. D. Adams, E. Braunwald, K. J. Isselbacher and R. G. Petersdorf, Harrison’s Principle of Internal Medicine, McGraw Hill Co, New York, (1977) p. 1088.
18. Gardiner JV, Kong WM, Ward H, Murphy KG, Dhillo WS, Bloom SR (2005) AAV mediated expression of anti-sense neuropeptide Y cRNA in the arcuate nucleus of rats results in decreased weight gain and food intake. BiochemBiophys Res Commun 327(4):1088–1093. doi:10.1016/j.bbrc.2004.12.113.
19. Gowri S, Chinnaswamy P. Evaluation of in vitro antimutagenic activity of Caralluma adscendens Roxb. In bacterial reverse mutation assay. J Nat Prod Plant Resour 2011;1:27-34.
20. Gupta S, Lakshmi JA and Prakash J. Effect of different blanching treatment on ascorbic acid retention in green leafy vegetables. Natural product radiance.;7(2):111-116. (2008).
21. Herborne JB. Phytochemical Methods 3 (ed) Chapman and Hall Ltd London, 1973; pp135-203.
22. Jadge DR, Naik JB. Anti-inflammatory Activity of Ethanolic and Aqueous Extracts of Caralluma adscendens. Journal of Pharmacy Research. 2009;2(7):1228-1229.
23. Joshi VC, Rao AS, Wang YH, Avula B, Khan IA. Authentication of Caralluma adscendens var. fimbriata (Wall.) Gravely & Mayur. Planta Med 2009; 75).
24. K. Dash, B. Mishra, A. Panda, C. P. Patro and S. Ganapathy, Indian J. Nat. Prod., 19, 24 (2003).
25. K. Dash, P. Suresh, S. K. Sahu, D. M. Kar, S. Ganapathy and S. B. Panda, J. Natural Remedies., 2, 182 (2002).
26. Kamil M, Fjayaraj A, Ahmad F, Gunasekhar C, Samuel S, Chan K, et al. (1999). Identification and quantification of flavonoids from Caralluma arabica and its quality control studies. J Pharm Pharmacol. 51(Suppl):225.14.
27. Kunert O, Rao VG, Babu GS, Sujatha P, Sivagamy M, Anuradha S, et al. Pregnane glycosides from Caralluma adscendens var. fimbriata. Chem Biodivers 2008; 5:239-50.
28. Kunert O, Rao VG, Babu GS, Sujatha P, Sivagamy M, AnuradhaS, Rao BV, Kumar BR, Alex RM, SchuhlyW, Kuhnelt D, Rao GV, Rao AV (2008) Pregnane glycosides from Caralluma adscendens var. fimbriata. ChemBiodivers 5(2):239–250. doi:10.1002/ cbdv.200890021.
29. Lawrence RM, Chaudhary S. (2004). Caralluma fimbriata in the treatment of obesity 12th Annu WConger on Antiaging medicine held on December 2-5, (Las vegas, NV USA).
30. Lawrence, R.M. and S. Choudhary. Caralluma fimbriata in the treatment of obesity 12th annual congress on anti-aging medicine. Winter session December 2-5. Las vegasNv USA 2004.
31. M. M. Cown, Clin. Microbiol. Rev., 12, 564 (1999).
32. Maheshu V, Priyadarsini DT, Sasikumar JM. Antioxidant capacity and amino acid analysis of Caralluma adscendens (Roxb.) Haw var. Fimbriata (wall.) Grav. And Mayur. Aerial parts. J Food Sci Technol 2014; 51:2415-24.
33. Maheshu V, Priyadarsini DT, Sasikumar JM. Antioxidant capacity and amino acid analysis of Caralluma adscendens (Roxb.) Haw var. Fimbriata (wall.) Grav. And Mayur. Aerial parts. J Food Sci Technol 2014; 51:2415-24.
34. Mahima Chauhan*, Vandana Garg, Ghazala Zia, Rohit Dutt. "Potential Role of Phytochemicals of Fruits and Vegetables in Human Diet". Research J. Pharm. and Tech. 13(3): March 2020: 1587-1589.
35. Mrs. Archana A. Bele, Dr. Anubha Khale. "An approach to a Nutraceutical". Research J. Pharm. and Tech. 6(10): October 2013: 1161-1164.
36. Naik JB, Jadge DR. Anti-bacterial and anti-fungal activity of Actiniopteris radiata and Caralluma adscendens. Int J Pharm Tech Res 2010;2:1751-3.
37. PallabMaity, DhananjayHansda, UdayBandyopadhyay, Dipak Kumar Mishra, Indian Journal of Experimental Biology, 2009,47, 849-861.
38. Preethi Pavithra. R, Dr. Jayashri. P. "Influence of Naturally Occurring Phytochemicals on Oral Health". Research J. Pharm. and Tech. 12(8): August 2019: 3979-3983.
39. Priya D, Rajaram K, Suresh Kumar. Intl J Pharm Res Develop; 3(10):105-110 (2011).
40. R. D. Vidyarthi, A Textbook of Zoology, 14th Ed., S. Chand and Co, New Delhi (1977) p. 329.
41. R. Jasmine, Sakthivel H(2015), Role of compounds from Terminalia chebula exhibiting AntiCholesterol property, International Journal of PharmTech Research, (2015), Vol.8, No.10, pp 210-215.
42. Ragavan Balliah, Monisha Sudhakar (2015), In Vitro Evaluation of Cytotoxic and Antiproliferative Activity of a Polyherbal Extract against H9c2 Cardiac Cells, International Journal of PharmTech Research, (2015), Vol.8, No.10, pp 191-197.
43. Ramesh M, Y.N. Rao, M.R. Kumar, A.V.N.A. Rao, M.C. Prabhakar and B.M. Reddy. Antinociceptive and anti-inflammatory activity of carumbelloside-I isolated from Caralluma umbellata. J. Ethnopharmacol 1999; 68: 349-352.
44. Robinka Khajuria, Loveleen Kaur, Aditi Kaushik and Gurpreet Saredia. "Evaluation of Antimicrobial and Phytochemical Properties of some Indigenous Indian plants". Research Journal of Pharmacognosy and Phytochemistry. 6(1): January-March, 2014, 5-8.
45. Rupa Bhattacharya, Prajakta Naitam. "Green Anticancer Drugs – A Review". Research Journal of Pharmacognosy and Phytochemistry. 11(4): October- December, 2019: 231-243.
46. S. Mathew, K. N. Patel and B. K. Shah, Indian J. Nat. Prod., 14, 11 (1995).
47. Sakore S, Patil SD, Surana S. Hypolipidemic activity of Caralluma adscendens on triton and methimazole induced hyperlipidemic rats. Pharmtechmedica 2012; 1:49-52.
48. Sheela. Proximate Composition of Underutilized Green Leafy Vegetables in Southern Karnataka. J Hum Ecol.; 15(3):227-229. (2004).