Author(s): Nowshin N. Rumzhum, Md. Mostafizur Rahman, Most. Nazma Parvin, Sadia A. Chowdhury

Email(s): Email ID Not Available

DOI: Not Available

Address: Nowshin N. Rumzhum*, Md. Mostafizur Rahman, Most. Nazma Parvin, Sadia A. Chowdhury
Laboratory of Pharmacognosy and Pharmacology, Department of Pharmacy, Stamford University Bangladesh, Dhaka-1217, Bangladesh
*Corresponding Author:

Published In:   Volume - 4,      Issue - 2,     Year - 2012


ABSTRACT:
The methanolic extract of leaves of Memecylon umbellatum (Melastomtaceae) was evaluated for in vitro antioxidant activity by determination of hydrogen peroxide scavenging activity, total antioxidant capacity, assay of nitric oxide scavenging activity and reducing power test and in vivo antinociceptive effect in acetic acid induced writhing model in Swiss albino mice. The plant extract was also subjected for brine shrimp lethality bio-assay to evaluate its cytotoxic property. The results revealed the presence of pronounced antioxidant property as compared with ascorbic acid used as standard and a dose-dependent (250 and 500 mg/kg) analgesic effect. Investigation also showed that it has strong lelthality (LC50 1.178 µg/ml) against brine shrimp nauplii, Vincristine Sulphate was used as positive control. The antioxidant, antinociceptive and cytotoxic properties observed seem to be in good accordance with the traditional uses of Memecylon umbellatum.


Cite this article:
Nowshin N. Rumzhum, Md. Mostafizur Rahman, Most. Nazma Parvin, Sadia A. Chowdhury. Evaluation of Antioxidant, Antino Potentialities of Methanolic Extract of Memecylon umbellatum. Research J. Pharmacognosy and Phytochemistry 2012; 4(2): 84-88.

Cite(Electronic):
Nowshin N. Rumzhum, Md. Mostafizur Rahman, Most. Nazma Parvin, Sadia A. Chowdhury. Evaluation of Antioxidant, Antino Potentialities of Methanolic Extract of Memecylon umbellatum. Research J. Pharmacognosy and Phytochemistry 2012; 4(2): 84-88.   Available on: https://rjpponline.org/AbstractView.aspx?PID=2012-4-2-6


Recomonded Articles:

Author(s): Bapu R. Thorat

DOI: 10.5958/0975-4385.2018.00017.1         Access: Open Access Read More

Author(s): S.D Mankar, M.S. Bhosale, Mohini Shelke, Pankaj Sonawane

DOI: 10.5958/0975-4385.2021.00007.8         Access: Open Access Read More

Author(s): Baviskar H. P., Dhake G. T., Kasai M. A., Chaudhari N. B., Deshmukh T. A.

DOI: 10.5958/0975-4385.2017.00024.3         Access: Open Access Read More

Author(s): Shifali Thakur, Bhawna Walia, Gitika Chaudhary

DOI: 10.52711/0975-4385.2021.00024         Access: Open Access Read More

Author(s): Buchake V.V., Bachhav R.S., Rode R.B., Aher S.S., Muthal A.P., Dhokchawle B.V. , Saudagar R.B.

DOI:         Access: Open Access Read More

Author(s): Alimuddin Saifi, Rajani Chauhan, J Dwivedi

DOI:         Access: Open Access Read More

Author(s): K Amutha , D Victor Arokia Doss

DOI:         Access: Open Access Read More

Author(s): Praveen S Nayak, Shweta Nayak, Ranjan Shety, P Das

DOI:         Access: Open Access Read More

Author(s): S C Baviya, R Radha, N Jayshree

DOI: 10.5958/0975-4385.2015.00038.2         Access: Open Access Read More

Author(s): Puneet Kumar Rai, Dev Raj Sharma, Amit Sharma

DOI: 10.5958/0975-4385.2015.00029.1         Access: Open Access Read More

Author(s): Kalpana Patil, Swati Dhande, Vilasrao Kadam

DOI:         Access: Open Access Read More

Author(s): Raje VN, Yadav AV, Shelar PA

DOI:         Access: Open Access Read More

Author(s): Shirisha K, Priyanka B, Habibur Rahman, Dipankar Bardalai, Fulchan Ali

DOI:         Access: Open Access Read More

Author(s): Shantha Sheela Nagarajan, Muthusamy Periyanna, Radha Ramalingam

DOI: 10.5958/0975-4385.2015.00036.9         Access: Open Access Read More

Author(s): AK Meena, Uttam S Niranjan, AK Yadav, Brijendra Singh, AK Nagaria, A Gaurav, MM Rao

DOI:         Access: Open Access Read More

Author(s): Mohd Asif, Mohd Wasim Ahmed, Shahidul Khair, Murugeswaran R, Rampratap Meena, Mokhtar Alam, Shoeb Ahmed Ansari, Mohd Tariq, Rakesh Kumar Negi

DOI: 10.5958/0975-4385.2019.00035.9         Access: Open Access Read More

Author(s): Nayana Devidas Patil

DOI:         Access: Open Access Read More

Author(s): V. Krishna Murthy Naik, K. Sudhakar Babu, J. Latha, Beulah Kolluru

DOI: 10.5958/0975-4385.2018.00013.4         Access: Open Access Read More

Author(s): KP Sampath Kumar, Debjit Bhowmik, Biswajit, Chiranjib, Pankaj, KK Tripathi, Margret Chandira

DOI:         Access: Open Access Read More


Recent Articles




Tags