Author(s): Vaishnavi Bhoite, Sachin Wagh

Email(s): vaishnavibhoite015@gmail.com

DOI: 10.52711/0975-4385.2024.00051   

Address: Vaishnavi Bhoite, Sachin Wagh
Delonix Society Baramati College of Pharmacy. Baramati MS.
*Corresponding Author

Published In:   Volume - 16,      Issue - 4,     Year - 2024


ABSTRACT:
Mucuna pruriens, a tropical legume, has garnered attention for its therapeutic potential, particularly due to its high L-DOPA content, a precursor to the neurotransmitter dopamine. This review paper synthesizes current research on the pharmacological properties of Mucuna pruriens, emphasizing its application in treating neurological disorders such as Parkinson’s disease. Traditional uses in various indigenous medicine systems have been validated through modern scientific methods, demonstrating significant anti-parkinsonian potential without the common side effects associated with synthetic L-DOPA. The analysis extends to the agronomic practices essential for its cultivation, which highlights the plant's dual role in sustainable agriculture and therapeutic applications. This review also addresses the critical aspects of toxicity and safety profiles, elaborating on the appropriate dosages and preparations to mitigate side effects commonly associated with natural products. Furthermore, the economic implications of Mucuna pruriens in the pharmaceutical industry are discussed, underlining its potential as a cost-effective treatment option. Comparative studies with other natural sources of L-DOPA offer a comprehensive overview of its advantages over synthetic alternatives, providing insights into its higher efficacy and lower toxicity. The review concludes with suggestions for future research directions, particularly in genetic variability, which could pave the way for enhanced therapeutic profiles tailored to individual needs. This paper aims to contribute to the broader understanding of Mucuna pruriens, encouraging further clinical and agronomic research to fully exploit its potential.


Cite this article:
Vaishnavi Bhoite, Sachin Wagh. Boost Your Mood with Mucuna pruriens. Research Journal of Pharmacognosy and Phytochemistry.2024; 16(4):278-1. doi: 10.52711/0975-4385.2024.00051

Cite(Electronic):
Vaishnavi Bhoite, Sachin Wagh. Boost Your Mood with Mucuna pruriens. Research Journal of Pharmacognosy and Phytochemistry.2024; 16(4):278-1. doi: 10.52711/0975-4385.2024.00051   Available on: https://rjpponline.org/AbstractView.aspx?PID=2024-16-4-15


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2.    Dhanasekaran, M., Tharakan, B., and Manyam, B. V. Anti-Parkinson Drug - Mucuna pruriens Shows Promise. Phytotherapy Research. 2008; 22(1), 6-11. doi: 10.1002/ptr.2251.
3.    Misra, L., and Wagner, H. Extraction of Bioactive Principles from Mucuna pruriens Seeds. Indian Journal of Biochemistry and Biophysics. 2007; 44(1): 56-60.
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