Research Journal of Pharmacognosy and Phytochemistry

ISSN

0975-4385 (Online)
0975-2331 (Print)


Submit Article

Hepatoprotective Activity of Tamarindus indica on Liver Damage Caused by Thioacetamide

Author(s): Pradeep Kumar Samal

Email(s): samalpharmacology@rediffmail.com

DOI: Not Available

Address: Pradeep Kumar Samal*
SLT Institute of Pharmaceutical Sciences, Guru Ghasidas Vishwavidyalaya, Bilaspur, Chhattisgarh.
*Corresponding Author:

Published In:   Volume - 5,      Issue - 3,     Year - 2013

 View HTML        View PDF

ABSTRACT:
The objective of this study was to investigate the hepatoprotective activity of Tamarindus indica seeds against thioacetamide induced hepatic damage in rats. The plant material were dried in shade then powdered and extracted with methanol. Preliminary phytochemical tests were done. Methanolic extract of Tamarindus indica seeds showed presence of phenolic compound and flavanoids. The degree of protection was measured by using biochemical parameters like serum glutamate oxaloacetate transaminase (SGOT), serum glutamate pyruvate transaminase (SGPT), alkaline phosphatase (ALP), bilirubin (BRN), and total protein (TP). Alteration in the levels of biochemical markers of hepatic damage like SGOT, SGPT, ALP, Bilirubin and total protein were tested in both thioacetamide treated and untreaed groups. Thioacetamide has enhanced the SGOT, SGPT, ALP and bilirubin and decrease Total Protein level in liver. Treatment of methanolic extract of Tamarindus indica seeds (500mg/kg) has brought back the altered levels of biochemical markers to the near normal levels in the dose dependent manner. Our findings suggested that Tamarindus indica methanol seeds extract possessed hepatoprotective activity. Silymarin was used as reference standard.


Keywords:

Cite this article:
Pradeep Kumar Samal. Hepatoprotective Activity of Tamarindus indica on Liver Damage Caused by Thioacetamide . Research J. Pharmacognosy and Phytochemistry 2013; 5(3): 123-126.

Cite(Electronic):
Pradeep Kumar Samal. Hepatoprotective Activity of Tamarindus indica on Liver Damage Caused by Thioacetamide . Research J. Pharmacognosy and Phytochemistry 2013; 5(3): 123-126.   Available on: https://rjpponline.org/AbstractView.aspx?PID=2013-5-3-3


Recomonded Articles:

Night Jasmine (Nyctanthes arbortristis)

Author(s): Anshuman Singh, Bhupendra Vyas

DOI: 10.5958/0975-4385.2018.00052.3         Access: Open Access Read More

Review on Celosia argentea L. Plant

Author(s): Bapu R. Thorat

DOI: 10.5958/0975-4385.2018.00017.1         Access: Open Access Read More

Mentha arvensis (Pudina): A Review Based upon its Medicinal Properties

Author(s): Shifali Thakur, Bhawna Walia, Gitika Chaudhary

DOI: 10.52711/0975-4385.2021.00024         Access: Open Access Read More

Phytochemical Investigation on Vinca rosea by Thin Layer Chromatography

Author(s): Gomathi B , Anuradha R

DOI:         Access: Open Access Read More

Phytochemical Studies of Seeds of Tamarindus indica

Author(s): Gaurav Kumar, Indu Sharma

DOI:         Access: Open Access Read More

Pharmacognostical Studies on Leaves of Allamanda cathartica with Detail Physicochemical and Phytochemical Evaluation

Author(s): Kirteebala P Pawar, Milind J Bhitre, Priyanka V Kalamkar, Mohan K Kale

DOI: 10.5958/0975-4385.2015.00013.8         Access: Open Access Read More

A Review on Ficus hispida

Author(s): Vidula Salvi, Yadunath Joshi, Swati Dhande , Vilasrao Kadam

DOI:         Access: Open Access Read More

Therapeutic Swertia chirata - An Overview

Author(s): Kalpana Patil, Swati Dhande, Vilasrao Kadam

DOI:         Access: Open Access Read More

Phytochemistry and Pharmacology of an Important Indian Medicinal Plant Crataeva nurvala Buch Ham

Author(s): Soosamma John, Madhavi T., Bincy Raj, Jincy Shaji, Vinutha

DOI:         Access: Open Access Read More

Coccinia indica- A Phytopharmacological Review.

Author(s): Raje VN, Yadav AV, Shelar PA

DOI:         Access: Open Access Read More

Anogeissus latifolia-An Overview

Author(s): Ravi Dubey, Saba Shaikh, Swati Dhande, Y. M. Joshi, Vilasrao J. Kadam

DOI:         Access: Open Access Read More

An Overview - Royal Poinciana

Author(s): Shantha Sheela Nagarajan, Muthusamy Periyanna, Radha Ramalingam

DOI: 10.5958/0975-4385.2015.00036.9         Access: Open Access Read More

Vitex negundo Linn; a Review on Its Ethnobotany, Phytochemical and Pharmacological Profile

Author(s): AK Meena, Uttam S Niranjan, AK Yadav, Brijendra Singh, AK Nagaria, A Gaurav, MM Rao

DOI:         Access: Open Access Read More

Comparative Antimicrobial Studies of Methanolic Extract of Muntingia calabura, Basella alba and Basella rubra Leaves.

Author(s): K.B. Premakumari, Ayesha Siddiqua, Shanaz Banu, J. Josephine, Leno Jenita , Bincy Raj

DOI:         Access: Open Access Read More

A Review on Medicinal Uses and Pharmacological Effects of Cleome viscosa

Author(s): Lenkalapally Matsyagiri, Kommu Sudhakar, Takkadpelliwar Santoshi, Masna Nagarjuna , N. L. Gowrishankar

DOI:         Access: Open Access Read More

Antimitotic activity of Borassus flabellifer Seed Coat

Author(s): Gottumukkala Krishna Mohan, Malavika Yadav, M Sandhya Rani, Kalakotla Shanker

DOI: 10.5958/0975-4385.2016.00033.9         Access: Open Access Read More

A Review on Zanthoxylum alatum Roxb.

Author(s): Umesh Annappan, Vijaya Bharathi Rajkishore, Radha Ramalingam

DOI: 10.5958/0975-4385.2015.00034.5         Access: Open Access Read More

Standardization of the Corn silk (Zea mays Linn.)

Author(s): Hayat M. Mukhtar, Sandeep Singh, Harjas Kaur, Manwinder Singh

DOI:         Access: Open Access Read More

Formulation and In-Vitro Evaluation of Sun Protection Factor of Methanolic Extract of Zanthoxylum rhetsa DC. Sunscreen lotion.

Author(s): Shantanu S. Kale, Amol H. Rajmane. Vaibhav C. Urunkar. Megha K. Gaikwad, Snehal B. Bhandare

DOI:         Access: Open Access Read More

Phytochemical Screening of Components Present Floral Essential oil of an Indigenous Variety of Lantana camara, Linn (Verbenaceae)

Author(s): Swagatika Pradhan, Smaranika Pattnaik

DOI: 10.5958/0975-4385.2017.00037.1         Access: Open Access Read More

Research Journal of Pharmacognosy and Phytochemistry (RJPP) is an international, peer-reviewed journal, devoted to pharmacognosy...... Read more >>>

RNI: Not Available                     
DOI: 10.5958/0975-4385 

Quick Links


Latest Issues

Popular Articles


Recent Articles



An Evaluation of the Medicinal Value of Solanum nigrum L and Solanum torvum Sw.
Formulation and Evaluation of Herbal Hand Sanitizer
Formulation and Evaluation of Nutraceutical Capsules
Lantana Camara Linn: A Review on Chemical Constituents and Medicinal Approach
Phytosomes: An Emerging Drug Delivery System
Remediation Strategies of Xenobiotics in Urban Soils and Water: A Review
A Brief Review Article on Carica papaya and its Medical Advantages
A Comprehensive Review on Phytochemicals and Pharmacological Activities of Digera muricata (L.)
Formulation and Evaluation of Herbal Cream for Depigmentation
Pharmacognostical Evaluation, In-vitro Anti-Inflammatory and Anti-Arthritic Activities of Sageraea laurina Dalzell
A Review on Traditional uses, Bioactive Chemical Constituents, Pharmacology, and Toxicity of Tinospora cordifolia (Guduchi or Giloy)
The Science behind Ashwagandha: A Review of its Therapeutic Potential
An Inspiration to Modern Medicines: A Review
A overview on Pharmaceutical Application of Tree Tea Oil
A Review on Treatment of Leprosy by using Medicinal Plants
An Overview on Kidney Stone Based on Medicinal Plants
A Review Article on the Formulation and Evaluation of Herbal Hair Oil
Formulation and Evaluation of Anti-diabetic Herbal Tablet containing Syzygium cuminii, Swertia chirata and Gymnema sylvestre
Pharmacognostic, Physicochemical and Phytochemical Evaluation of The Leaves of Basella rubra Linn. (Basellaceae)
ADME Studies of Phytochemicals in Stachys pilifera Benth plant species

Tags


About Journal

Research Journal of Pharmacognosy and Phytochemistry (RJPP) (ISSN: print-0975-2331, Online-0975-4385) is an international, peer-reviewed journal, devoted to pharmacognosy. The aim of RJPP is to increase the impact of pharmacognostic research both in academia and industry, with strong emphasis on quality and originality. RJPP publishes Original Research Articles, Short Communications, Review Articles in all areas of Pharmacognosy and Phytochemistry.

The journal is published quaterly every year in last week of March, June, September and December.    
Read More  

Visitors

Today: 48
Yesterday: 1051
Total: 1043894