Keshav Chandravanshi, Manisha Sahu, Raju Sahu, Neelima Sahu, Sweety Lanjhiyana, Anish Chandy
Keshav Chandravanshi*, Manisha Sahu, Raju Sahu, Neelima Sahu, Sweety Lanjhiyana, Anish Chandy
School of Pharmacy, Chouksey Engineering Collage, Lalkhadan, Bilaspur, Chhattisgarh, India.
Volume - 14,
Issue - 3,
Year - 2022
In current scenario pharmaceutical dosage forms contain many additives besides the active ingredients to assist manufacturing and to obtain the desired effect to the pharmaceutical active ingredientsPlant Mucilages are pharmaceutically important polysaccharide with wide range of applications such as thickening, binding, disintegrating, suspending, emulsifying, stabilizing and gelling agents. Naturally availablemucilages are preferred to synthetic materials due to their non toxicity, low cost, emollient and non-irritating nature. The synthetic polymers have certain disadvantages such as high cost, toxicity, environmental pollution during synthesis, non-renewable sources, side effects, less patient compliance, etc. mucilages are potent candidate to be used in various pharmaceutical formulations as a potential candidate for novel drug delivery system (NDDS). In this review, we describe the developments in natural gums, mucilages and Pectins for use in the pharmaceutical sciences.
Cite this article:
Keshav Chandravanshi, Manisha Sahu, Raju Sahu, Neelima Sahu, Sweety Lanjhiyana, Anish Chandy. Isolation of Mucilage from Herbal plants and its Evaluation as a Pharmaceutical Excipients. Research Journal of Pharmacognosy and Phytochemistry. 2022; 14(3):171-8. doi: 10.52711/0975-4385.2022.00031
Keshav Chandravanshi, Manisha Sahu, Raju Sahu, Neelima Sahu, Sweety Lanjhiyana, Anish Chandy. Isolation of Mucilage from Herbal plants and its Evaluation as a Pharmaceutical Excipients. Research Journal of Pharmacognosy and Phytochemistry. 2022; 14(3):171-8. doi: 10.52711/0975-4385.2022.00031 Available on: https://rjpponline.org/AbstractView.aspx?PID=2022-14-3-5
1. Chandrima Chatterjee*, SoniaAuddy and Surabhi Chaudhuri Isolation and Characterization of Mucilage from Abroma Augusta and Its Application in Pharmaceutical Suspension Preparation, 2016; 8(4): 1-3
2. Sumanta Mondal, Syed Tazib Rahaman an Overview on Isolation and Characterization of Mucilage from Various Species Related to Various Plant Families, 2018; 4(2): 284-288
3. Smita Kolhe, Tejal Kasar, S.N. Dhole and Mohini Upadhye Extraction of Mucilage and Its Comparative Evaluation as A Binder, 2014; 2(3): 330-343
4. Vuyyuri Bhaargavi, G.S.L. Jyotsna and Reshma Tripurana A Review on Hepatoprotective Activity, 2014; 5(3): 690-702
5. M. Ravindrakullai Reddy and Kopparam Manjunath Pharmaceutical Applications of Natural Gums, Mucilages and Pectins - A Review, 2013; 2(3): 1233-1239
6. Baliga, M. S., Shivashankara, A. R., Haniadka, R., Dsouza, J., and Bhat, H. P. (2011). Phytochemistry, nutritional and pharmacological properties of Artocarpus heterophyllus Lam (jackfruit): A review. Food Research International, 44(7): 1800- 1811.
7. Chowdhury, M., Sengupta, A., Datta, L., and Chatterjee, S. Role of mucilage as pharmaceutical additives and cytoprotective agent.
8. Divekar Varsha, B., and Mohan, K. (2010). Isolation and characterization of mucilage from lepidium sativum linnseeds. Internaional journal of pharma research and development, 2, 1-5.
9. Sunil, M., Biswal, P. K., Mishra, B., and Sahoo, S. (2010). Isolation, characterization and pharmaceutical evaluation of the mucilage from Polyalthia suberosa leaves. International Journal of PharmTech Research, 2(2); 1455-1459.
10. Alalor, C. A., Avbunudiogba, J. A., and Augustine, K. (2014). Isolation and Characterization of Mucilage Obtained from Colocasia Esculenta. International Journal of pharma and bio sciences, 4(1): 25-29.
11. Hamman JH and Tarirai C: Functional excipients. Chem Today 2006; 24: 57-62.
12. Shirwaikar A and Prabhu SL: Herbal excipients in novel drug delivery systems. Indian Journal of Pharmaceutical Science 2008; 70: 415-422.
13. Beneke CE, Viljoen AM and Hamman JH: Polymeric plant derived excipients in drug delivery. Molecules 2009; 14: 2602-2620.
14. Stephen AM and Churms SC: Food polysaccharides and their applications. Taylor and Francies, CRC Press, New York, Edited by Stephen AM, Phillips GO and Williams PA, 2006: 1-24.
15. Koleng JJ, McGinity JW and Wiber WR: Handbook of pharmaceutical excipients. Pharmaceutical Press, Edition 6, Edited by Raymond C Rowe, Paul J Sheskey and Marian E Quinn, 2009: 1-3.
16. Kokate CK, Purohit AP and Gokhale SB: A Textbook of Pharmacognosy. Nirali Prakashan, Pune, Edition, 2003; 22: 136-139.
17. Kottke KM: Modern Pharmaceutics. Marcel Dekker, New York, 2002: 287-333.
18. Richardson PH, Willmer J and Foster TJ: Dilute solution properties of guar and locust bean gum in sucrose solutions. Food Hydrocolloid 1998; 12: 339- 348.
19. Evans WC, Trease and Evans: Pharmacognosy. Harcourt Brace and Co., Asia Pvt. Ltd, Singapore, Edition, 1996; 14: 196-208, 213-215.
20. Edward MR: Modern Pharmaceutics. Marcel Dekker, New York, 2002; 287-298.
21. Aslam A and Parrott E: Effect of aging on some physical properties of hydrochlorothiazide tablets. Journal of Pharmaceutical Science 1971; 60: 263-266.
22. Kokate CK, Purohit AP and Gokhale SB: A Textbook of Pharmacognosy. Nirali Prakashan, Pune, Edition, 2003; 21: 147-154, 157.
23. Rangari VD: Pharmacognosy and Phytochemistry. Career Publication, Nashik, India, 2006; 400-444.
24. Kulkarni GT: Microwave assisted fast extraction of mucilages and Pectins. Indian Journal of Pharmaceutical Education and Research 2009; 43: 260-265.
25. Ofoefule SI and Chukwu A: Application of Abelmoschus esculents gum as a mini-matrix for furosemide and diclofenac sodium tablets. Indian Journal of Pharmaceutical Science 2001; 63: 532-535.
26. Oluwatosin AO: Assessment of Albiziazygia gum as a binding agent in tablet formulations. Acta Pharmaceutica 2005; 55: 263–276.
27. Patel MM, Chauhan GM and Patel LD: Mucilage of lepidiumsativum, Linn (Asario) and Ocimum canum, sims. (Bavchi) as emulgents. Indian Journal of Hospital Pharmacy 1987; 24: 200-202.
28. Pawar H and D’mello PM: Isolation of seed gum from Cassia tora and preliminary studies of its applications as a binder for tablets. Indian Drugs 2004; 41: 465- 468.
29. Jani GK, Shah DP and Jain VC: Evaluating mucilage from Aloe barbadensis Miller as a pharmaceutical excipient for sustained-release matrix tablets. Pharmaceutical Technology 2007; 31: 90-98.
30. Owen SC: Handbook of pharmaceutical excipients. Pharmaceutical Press, Edited by Raymond CR, Paul JS and Marian EQ, Edition, 2009; 6: 782.
31. R. Malviya, “Extraction characterization and evaluation of selected mucilage as pharmaceutical excipient,”, 2011; 41(1): 39–44
32. Kirtikar KR, Basu BD. Indian Medicinal Plants. Delhi: Periodical expert’s book agency; 1991:1028.