Author(s): Umair Akhtar, Anjali M. Wankhade, Jugalkishor V. Vyas, Vivek V. Paithankar

Email(s): umairakhtar1999@gmail.com

DOI: 10.52711/0975-4385.2023.00021   

Address: Umair Akhtar*, Anjali M. Wankhade, Jugalkishor V. Vyas, Vivek V. Paithankar
Department of pharmacology, Vidyabharati College of Pharmacy, C.K. Naidu Road, Camp, Amravati-444602 (Maharashtra) India.
*Corresponding Author

Published In:   Volume - 15,      Issue - 2,     Year - 2023


ABSTRACT:
Since 5000 BC, medicinal plants have been used in India as part of the Ayurvedic medical system. Medical professionals frequently use herbal remedies. Taraxacum officinale, commonly called dandelion, is a perennial plant belonging to the family Asteraceae. It is also known as wet-a-bed, lion’s tooth, priest’s crown, blowball, milk gowan, wild endive, white endive, puffball, and Irish daisy. Long and upright flowering stalks with a single terminal inflorescence are present. It has numerous medicinal properties due to phytochemicals found in the plant's flower, leaf, stem, and roots. Sesquiterpenes found in dandelion root extracts. The root also includes a number of phenolic substances. The two sesquiterpenes taraxinic acid b-Dglucopyranoside and 11, 13-dihydrotaraxinic acid b-Dglucopyranoside An extract of combined dandelion leaves and flowers has been found to contain a number of flavonoid glycosides. Dandelion roots and leaves have historically been used to treat liver issues. Additionally, Native Americans used dandelion to treat heartburn, swelling, skin issues, kidney disease, and upset stomach. Research has been conducted to back up the descriptions of taraxacum that have been made so far. Up to doses of 10 g/kg (per oral) and 4 g/kg (intraperitoneal) of dried drug -per kilogramme body weight- in rats and mice, ethanolic extracts demonstrated very low toxicity.


Cite this article:
Umair Akhtar, Anjali M. Wankhade, Jugalkishor V. Vyas, Vivek V. Paithankar. A Review on: Phytoconstituents, Traditional and Medicinal uses of Taraxacum offinale (Dandelion). Research Journal of Pharmacognosy and Phytochemistry. 2023; 15(2):139-4. doi: 10.52711/0975-4385.2023.00021

Cite(Electronic):
Umair Akhtar, Anjali M. Wankhade, Jugalkishor V. Vyas, Vivek V. Paithankar. A Review on: Phytoconstituents, Traditional and Medicinal uses of Taraxacum offinale (Dandelion). Research Journal of Pharmacognosy and Phytochemistry. 2023; 15(2):139-4. doi: 10.52711/0975-4385.2023.00021   Available on: https://rjpponline.org/AbstractView.aspx?PID=2023-15-2-7


REFERENCES:
1.    Kumar Srivastava, Akhileshwar, Synthesis of Medicinal Agents from Plants, Significance of medicinal plants in human life, 1–24, (2018).
2.    Gautam, V., Raman, R.M.V., Ashish, K., Exporting Indian healthcare (Export po¬tential of Ayurveda and Siddha products and services) Road beyond boundaries (The case of selected Indian healthcare systems). Export-Import Bank of India, Mumbai, pp. 4–54, (2003).
3.    Bamola, Neelam and Verma, Poonam & Negi, Chandranandani. A Review on Some Traditional Medicinal Plants. International Journal of Life-Sciences Scientific Research, (2018).
4.    Di Napoli, A., Zucchetti, P. A comprehensive review of the benefits of Taraxacum officinale on human health. Bull Natl Res Cent 45, 110 (2021).
5.    Escudero, N., De Arellano, M., Fernández, S. et al. Taraxacum officinale as a food source. Plant Foods Hum Nutr 58, 1–10 (2003).
6.    All, Flower, leaves, root, shoots, dandelion (Taraxacum officinale), Available at http://www.naturalherbs.ro/project/ dandelion-taraxacum-officinale/
7.    Murray, Michael T. Textbook of Natural Medicine, Taraxacum officinale (Dandelion). 2020; 876–878.e1.
8.    Natalie Cortés, Cristina Mora, Katalina Muñoz, Jaiber Díaz, Raquel Serna, Dagoberto Castro, Edison Osorio, Microscopical descriptions and chemical analysis by HPTLC of Taraxacum officinale in comparison to Hypochaeris radicata: a solution for mis-identification, Revista Brasileira de Farmacognosia, 2014; 24(4): 381-388
9.    A.C. Schoenfelder, J.G. Bishop, H.M. Martinson, W.F. Fagan Resource use efficiency and community effects of invasive Hypochaeris radicata (Asteraceae) during primary succession Am. J. Bot., 97 (2010), pp. 1772-1779.
10.    O. Adedeji, O.A. Jewoola Importance of leaf epidermal characters in the Asteraceae family Not. Bot. Hort. Agrobot. Cluj., 36 (2008), pp. 7-16.
11.    Mary H. Dyer, Credentialed Garden Writer, Dandelion Flower Varieties: Interesting Types Of Dandelion Plants To Grow, from Gardening Know How: https://www.gardeningknowhow.com
12.    Noori, Omar & Mohammed noori jassim, Abdulkadir & Farhan, Safana, Identification of Dandelion Taraxacum officinale Leaves Components and Study Its Extracts Effect on Different Microorganisms. Journal of Al-Nahrain University, (2012), 15. 7-14.
13.    Huber, M., et al. Identification, quantification, spatiotemporal distribution and genetic variation of major latex secondary metabolites in the common dandelion (Taraxacum officinale agg.). Phytochemistry (2015)
14.    Di Napoli, A., Zucchetti, P. A comprehensive review of the benefits of Taraxacum officinale on human health. Bull Natl Res Cent 45, 110 (2021).
15.    Fonyuy E. Wirngo, Max N. Lambert, and Per B. Jeppesen, The Physiological Effects of Dandelion (Taraxacum Officinale) in Type 2 Diabetes, The Review of diabetic studies (2016), Vol. 13 ⋅ No. 2-3.
16.    Marta González-Castejón, Francesco Visioli, Arantxa Rodriguez-Casado, Diverse biological activities of dandelion, Nutrition Reviews, 2012; 70(9): 534–547,
17.    Schutz K, Kammerer DR, Carle R, et al. Characterization of phenolic acids and flavonoids in dandelion (Taraxacum officinale WEB. ex WIGG.) root and herb by high-performance liquid chromatography/electrospray ionization mass spectrometry. Rapid Commun Mass Spectrom. 2005; 19: 179–186.
18.    Hagymasi K, Blazovics A, Feher J, et al. The in vitro effect of dandelion’s antioxidants on the microsomal lipid peroxidation. Phytotherapy Res. 2000; 14: 43– 44.
19.    Budzianowski J. Coumarins, caffeoyltartaric acids and their artifactual methyl esters from Taraxacum officinale leaves. Planta Med. 1997; 63: 288–289.
20.    Kristo SZT, Ganzler K, Apati P, et al. Analysis of antioxidant flavonoids from Asteraceae and Moraceae plants by capillary electrophoresis. Chromatographia. 2002; 56:121–126.
21.    Sweeney, Brooke, et al. "Evidence-based systematic review of dandelion (Taraxacum officinale) by natural standard research collaboration." Journal of herbal pharmacotherapy 5.1 (2005): 79-93.
22.    [Internet] Available at, https://www.mountsinai.org/health-library/herb/dandelion.
23.    Choi U-K, Lee O-H, Yim JH, Cho C-W, Rhee YK, Lim S-I, Kim Y-C. Hypolipidemic and Antioxidant Effects of Dandelion (Taraxacum officinale) Root and Leaf on Cholesterol-Fed Rabbits. International Journal of Molecular Sciences. 2010; 11(1): 67-78.
24.    By Rachael Link, and Ansley Hill, 13 Emerging Health Benefits of Dandelion, Available from: https://www.healthline.com/nutrition/ dandelion-benefits.
25.    Katrin Schütz; Reinhold Carle; Andreas Schieber (2006). Taraxacum—A review on its phytochemical and pharmacological profile., 107(3), 0–323.
26.    Li Y, Chen Y, Sun-Waterhouse D. The potential of dandelion in the fight against gastrointestinal diseases: A review. J Ethnopharmacol. 2022 Jul 15; 293:115272.
27.    A. Bhattacharyya et al. Oxidative stress: an essential factor in the pathogenesis of gastrointestinal mucosal diseases Physiol. Rev. (2014)
28.    Gao C, Kong S, Guo B, Liang X, Duan H, Li D. Antidepressive Effects of Taraxacum Officinale in a Mouse Model of Depression Are Due to Inhibition of Corticosterone Levels and Modulation of Mitogen-Activated Protein Kinase Phosphatase-1 (Mkp-1) and Brain-Derived Neurotrophic Factor (Bdnf) Expression. Med Sci Monit. 2019 Jan 13; 25: 389-394.
29.    Sharma K, Zafar R. Optimization of methyl jasmonate and β-cyclodextrin for enhanced production of taraxerol and taraxasterol in (Taraxacum officinale Weber) cultures. Plant Physiol Biochem. 2016; 103: 24–30.
30.    Yousefi Ghale-Salimi, Mahboubeh; Eidi, Maryam; Ghaemi, Nasser; Khavari-Nejad, Ramezan Ali, Inhibitory effects of taraxasterol and aqueous extract of Taraxacum officinale on calcium oxalate crystallization: in vitro study. Renal Failure, 2018; 40(1): 298–305.
31.    Mahboubi M, Mahboubi M. Hepatoprotection by dandelion (Taraxacum officinale) and mechanisms. Asian Pac J Trop Biomed 2020; 10(1): 1-10.
32.    Ghorbel Koubaa F, Chaâbane M, Choura B, Turki M, Makni-Ayadi F, El Feki A. Hepatoprotective Effects of Taraxacum officinale Root Extract on Permethrin-induced Liver Toxicity in Adult Mice. Pharm Biomed Res 2020; 6(3): 223-236
33.    Yang Y, Ying G, Wu S, Wu F, Chen Z (2020) In vitro inhibition effects of hepatitis B virus by dandelion and taraxasterol. Infect Agents Cancer 15(44): 1–10
34.    Diaz K, Espinoza L, Madrid A, Pizarro L, Chamy R (2018) Isolation and identification of compounds from bioactive extracts of Taraxacum officinale Weber ex F. H. Wigg. (dandelion) as a potential source of antibacterial agents. Evid Based Complement Alternat Med. 8: 1–8.
35.    Qian L, Zhou Y, Teng Z, Du CL, Tian C. Preparation and antibacterial activity of oligosaccharides derived from dandelion. Int J Biol Macromol. 2014; 64: 392-4.
36.    Perumal, Nithiyaa, et al. "Synergistic antidiabetic activity of Taraxacum officinale (L.) Weber ex FH Wigg and Momordica charantia L. polyherbal combination." Biomedicine & Pharmacotherapy 145 (2022): 112401.
37.    Savych A, Bilyk O, Vaschuk V, Humeniuk I (2021) Analysis of inulin and fructans in Taraxacum officinale L. roots as the main inulin-containing component of antidiabetic herbal mixture. Pharmacia 68(3): 527–532
38.    Mir, M. Amin, S. S. Sawhney, and M. M. S. Jassal. "In-vitro antidiabetic studies of various extracts of Taraxacum officinale." The Pharma Innovation 4.1, Part B (2015): 61.
39.    Raghu Mohan Rao P. ;  Jyothi, Y.;  Rabban, S. I., Anti-obesity activity of Taraxacum officinale in high fat diet induced obese rats, Journal of Chemical and Pharmaceutical Research 2015 Vol.7 No.4 pp.244-248 ref.13.
40.    Aabideen ZU, Mumtaz MW, Akhtar MT, Mukhtar H, Raza SA, Touqeer T, Saari N. Anti-Obesity Attributes; UHPLC-QTOF-MS/MS-Based Metabolite Profiling and Molecular Docking Insights of Taraxacum officinale. Molecules. 2020; 25(21): 4935.
41.    Fulga, Ala, Pantea, Valeriana. Antioxidant activity of Taraxacum officinale. In: MedEspera: the 8th Internat. Medical Congress for Students and Young Doctors: abstract book. Chișinău: S. n., 2020, p. 267-268.
42.    Lis B, Jedrejek D, Rywaniak J, Soluch A, Stochmal A, Olas B (2020). Flavonoid preparations from Taraxacum officinale L. fruits—A phytochemical, antioxidant and hemostasis studies. Molecules. 25(5402): 1–33.
43.    Ingber A. Seasonal allergic contact dermatitis from Taraxacum officinale (dandelion) in an Israeli florist. Contact Dermatitis 2000; 43(1): 49.
44.    Dawe RS, Green CM, MacLeod TM, et al. Daisy, dandelion and thistle contact allergy in the photosensitivity dermatitis and actinic reticuloid syndrome. Contact Dermatitis 1996; 35(2): 109-110.
45.    Mark KA, Brancaccio RR, Soter NA, et al. Allergic contact and photoallergic contact dermatitis to plant and pesticide allergens. Arch Dermatol 1999; 135(1): 67-70.
46.    Rodriguez B, Rodriguez A, de Barrio M, et al. Asthma induced by canary food mix. Allergy Asthma Proc 2003; 24(4): 265-268.
47.    Bekhaled I, Benalia A, Mehida H, Meziani S, Tarfaoui L, Djjebar AA, Mai AH, Bensaid I, Demmouche A, Evaluation of the Acute Toxicity of Dandelion (Taraxacum officinale) Roots, Journal of Drug Delivery and Therapeutics. 2020; 10(3): 159-163
48.    Assessment report on Taraxacum officinale Weber ex Wigg., radix cum herba, EMA/HMPC/212897/2009.

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