Author(s): Bharadhan Bose, Sethuramani Amarnathan, Gopi Selvam

Email(s): b.barani143@gmail.com

DOI: 10.52711/0975-4385.2024.00016   

Address: Bharadhan Bose1,2*, Sethuramani Amarnathan2, Gopi Selvam2
1Sree Abirami College of Pharmacy, (Affiliated with The Tamil Nadu Dr. M. G. R. Medical University, Chennai) Coimbatore - 641021, Tamil Nadu, India.
2College of Pharmacy, Madurai Medical College, (Affiliated with The Tamil Nadu Dr. M. G. R. Medical University, Chennai) Madurai - 625020, Tamil Nadu, India.
*Corresponding Author

Published In:   Volume - 16,      Issue - 2,     Year - 2024


ABSTRACT:
Objectives: Morinda coreia has rich active components which has been used in folk medicine for the treatment of several diseases. Their active substance content may vary according to plant genetics, parts used,as well as to climatic factors, quality of the ground in which the plants were grown, the time of harvesting, and the extraction methods. Basically the flowers can heal the common cold, improve memory, aid relaxation due to presence of volatile oil. Flowers could be used as a new approach for the development of nutraceutical products or functional foods. The flower part of this plant are not documented. To develop and apply it, we report Pharmacological effects such as anti-inflammatory, antimicrobial activity. Methods: The extracts were prepared by cold maceration process with aqueous and organic solvents such as ethanol and ethyl acetate. The anti-inflammatory activity were evaluated using carrageenan-induced paw edema method and the antimicrobial activity by agar well diffusion method. Results: The maximum zone of inhibition for Bacillus subtilis was found to be more susceptible toward the ethanolic extract (14mm) at the maximum conc. of 300µl followed by ethyl acetate (10mm) and aqueous extract (12mm). Similarly for Klebsiella pneumonia maximum inhibitory zone (13mm) followed Pseudomonas auroginosa (13mm), Staphylococcus aureus (12mm), Candida albicans was moderate sensitive towards ethanolic extract (11mm) Conclusion: The ethanolic extract of Morinda coreia flower possessed high anti-inflammatory, antimicrobial activity than ethyl acetate and aqueous extracts on comparing with standards.


Cite this article:
Bharadhan Bose, Sethuramani Amarnathan, Gopi Selvam. Screening of Anti-inflammatory and Antimicrobial activity on Flower Extracts of Morinda coreia Buch Ham. Research Journal of Pharmacognosy and Phytochemistry. 2024; 16(2):83-8. doi: 10.52711/0975-4385.2024.00016

Cite(Electronic):
Bharadhan Bose, Sethuramani Amarnathan, Gopi Selvam. Screening of Anti-inflammatory and Antimicrobial activity on Flower Extracts of Morinda coreia Buch Ham. Research Journal of Pharmacognosy and Phytochemistry. 2024; 16(2):83-8. doi: 10.52711/0975-4385.2024.00016   Available on: https://rjpponline.org/AbstractView.aspx?PID=2024-16-2-5


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