Author(s):
T Sravani, K. Sunitha
Email(s):
sravisagar11@gmail.com
DOI:
10.52711/0975-4385.2023.00020 
Address:
T Sravani1*, K. Sunitha2
1,2Department of Pharmacognosy and Phytochemistry, Gitam Institute of Pharmacy, Gitam University, Rushikonda, Vishakapatnam - 530045, Andhra Pradesh, India.
*Corresponding Author
Published In:
Volume - 15,
Issue - 2,
Year - 2023
ABSTRACT:
Adiantum lunulatum (Hamsapadhi) is a cosmopolitan tropical fern that is traditionally employed in folklore medicine to address various maladies. The fern is a reservoir for major plant secondary metabolites like tannins, saponins, alkaloids, phenolics flavonoids, etc. Accredited the presence of phytochemicals the fern portrays pharmacological properties like antimicrobial, antifertility, hepatoprotective, anti-ulcerative, antipyretic, gastroprotective properties, etc. Despite numerous evidences of pharmacological applications in traditional medicines, there are very few in vitro and in vivo studies on the fern to corroborate its pharmacological properties and to appraise it as a prospective therapeutic agent, thus necessitating more research in this fern. The current review circumscribes the phytochemistry of the fern and its concomitant pharmacological properties.
Cite this article:
T Sravani, K. Sunitha. Ethnopharmacological properties of the fern Adiantum lunulatum: A Review. Research Journal of Pharmacognosy and Phytochemistry. 2023; 15(2):133-8. doi: 10.52711/0975-4385.2023.00020
Cite(Electronic):
T Sravani, K. Sunitha. Ethnopharmacological properties of the fern Adiantum lunulatum: A Review. Research Journal of Pharmacognosy and Phytochemistry. 2023; 15(2):133-8. doi: 10.52711/0975-4385.2023.00020 Available on: https://rjpponline.org/AbstractView.aspx?PID=2023-15-2-6
REFERENCES:
1. Jamshidi-Kia F, Lorigooini Z, Amini-Khoei H. Medicinal plants: Past history and future perspective. J HerbmedPharmacol. 2018; 7(1): 1–7. http://dx.doi.org/10.15171/jhp.2018.01
2. Thakkar S, Anklam E, Xu A, Ulberth F, Li J, Li B, et al. Regulatory landscape of dietary supplements and herbal medicines from a global perspective. RegulToxicolPharmacol. 2020; 114(104647): 104647. http://dx.doi.org/10.1016/j.yrtph.2020.104647
3. Zhang J, Wider B, Shang H, Li X, Ernst E. Quality of herbal medicines: challenges and solutions. Complement Ther Med. 2012; 20(1–2): 100–6. http://dx.doi.org/10.1016/j.ctim.2011.09.004
4. Yuan H, Ma Q, Ye L, Piao G. The traditional medicine and modern medicine from natural products. Molecules. 2016; 21(5): 559. http://dx.doi.org/10.3390/molecules21050559
5. Atanasov AG, Waltenberger B, Pferschy-Wenzig E-M, Linder T, Wawrosch C, Uhrin P, et al. Discovery and resupply of pharmacologically active plant-derived natural products: A review. Biotechnol Adv. 2015; 33(8): 1582–614. http://dx.doi.org/10.1016/ j.biotechadv.2015.08.001
6. Abdoulahi MII, Habibou HH, Abdelkader AS, Mborbe N, Chaibou M, Rahila HG, et al. Ethno Botanical, Pharmacology and Phytochemistry of widely used medicinal plants in Niger: A Review. J Med Plants Stud. 2022; 10(4): 46–60. http://dx.doi.org/10.22271/ plants.2022.v10.i4a.1436
7. Tomlinson TR, Akerele O. Medicinal plants: their role in health and biodiversity. University of Pennsylvania press; 2015.
8. DebjitBhowmik, Chiranjib, Pankaj, KK Tripathi, MR Chandira, KP Sampath Kumar. Zingiberofficinale the Herbal and Traditional Medicine and Its Therapeutically Importance. Research J. Pharmacognosy and Phytochemistry 2010; 2(2): 102-110.
9. Singh S, Singh DB, Singh S, Shukla R, Ramteke PW, Misra K. Exploring medicinal plant legacy for drug discovery in post-genomic era. ProcNatlAcadSci India Sect B Biol Sci. 2019; 89(4): 1141–51. http://dx.doi.org/10.1007/s40011-018-1013-x
10. Rastogi S, Pandey MM, Rawat AKS. Ethnopharmacological uses, phytochemistry and pharmacology of genus Adiantum: A comprehensive review. J Ethnopharmacol 2018; 215: 101–19. http://dx.doi.org/10.1016/j.jep.2017.12.034
11. Darshna Y Bhatt, S SPandya.Pharmacognostic and Preliminary Phytochemical Studies on the Leaf of Beta vulgaris Linn. (Chenopodiaceae)..Res. J. Pharmacognosy&Phytochem. 2015; 7(3): 163-166.
12. Search results — The Plant List. Theplantlist.org. [cited 2022 Oct 25]. Available from: http://www.theplantlist.org/tpl1.1/ search?q=Adiantum+lunulatum
13. Ravindra Singh, AakankshaTiwari. Adhatodavasica: A Miracle and Boon for Asthmatic people - A Review. Res. J. Pharmacognosy and Phytochem. 2016; 8(4): 242-244.
14. Jenat PJ, Suresh SN. Phytochemical analysis and antimicrobial activity of fern Adiantum lunulatum Burm. f. World J Pharm Res. 2018; 7(3): 640–8.
15. Goyal Rupendra Kumar, Jain Suman, DahimaRashmi. Indigenous Medicine used for Treatment of Diabetes in Gwalior Chambal Region of Madhya Pradesh. Research J. Pharm. and Tech. May 2013; 6(5): 589-591.
16. Bir SS, Irudayaraj V. Cytology of some ferns from the Nilgiris, South India-IV. Fern Gazette. 2001; 16(4): 177–90.
17. GoyalRupendra Kumar, Jain Suman, DahimaRashmi. Indigenous Medicine used for Treatment of Diabetes in Gwalior Chambal Region of Madhya Pradesh. Research J. Pharm. and Tech. May 2013; 6(5): 589-591.
18. Pratibha K, Otaghvari AM, Govindapyari H, Bahuguna YM, Uniyal PL. Some ethno-medicinally important pteridophytes of India.International Journal of Medicinal and Aromatic Plants. 2011; 1(1): 18–22.
19. ShobaSundaramoorthy, ShylajaGunasekaran, Uma Anitha, SathiaveluArunachalam, MythiliSathiavelu. Endophytes for Antimicrobial Activity- A Review. Research J. Pharm. and Tech. June, 2015; 8(6): 742-748.
20. Wursten B, Timberlake J, Darbyshire I. The Chimanimani Mountains: an updated checklist. Kirkia. 2017; 19(1).
21. Crouch NR, Klopper RR, Burrows JE, Burrows SM. Ferns of Southern Africa, A comprehensive guide Struik Nature Pages 426. 2011; 426–7.
22. ForoughTaheri, SaberAbbaszadeh, Ali Valibeik, EhsanSattari, ElhamGholami. The most important natural antioxidants and native herbs of Iran used in the nervous system as pre-anesthetics. Research J. Pharm. and Tech. 2019; 12(3): 1453-1456.
23. Gutierrez L. Adiantum lunulatum. Theferns.info. [cited 2022 Oct 27]. https://tropical.theferns.info/viewtropical.php?id=Adiantum+lunulatum
24. Hebbar MD(Ayu) JV. HamsapadiAdiantum lunulatum uses, research, remedies, side effects. Easy Ayurveda. Dr J V HebbarMD(Ayu); 2017 [cited 2022 Oct 28]. https://www.easyayurveda.com/2017/10/22/ hamsapadi-adiantum-lunulatum/
25. Burm F. Adiantum lunulatum Burm. f. — The Plant List [Internet]. Theplantlist.org. [cited 2022 Oct 29]. http://www.theplantlist.org/ tpl1.1/record/tro-26603272
26. Adiantum lunulatum Burm.Fil.Gbif.org. [cited 2022 Oct 30]. https://www.gbif.org/species/7173671/metrics
27. Sharma K, Kumar V, Kaur J, Tanwar B, Goyal A, Sharma R, et al. Health effects, sources, utilization and safety of tannins: a critical review. Toxin Rev 2021; 40(4): 432–44. http://dx.doi.org/10.1080/ 15569543.2019.1662813
28. Dias MC, Pinto DCGA, Silva AMS. Plant flavonoids: Chemical characteristics and biological activity. Molecules 2021; 26(17): 5377. http://dx.doi.org/10.3390/molecules26175377
29. S.S. Yadav, ParulSangwan, S. A. Ganie, S. S. Gulia. Studies on free radical Scavenging activity and total phenolic content of Foeniculumvulgare Mill. Research J. Pharm. and Tech. 2020; 13(7): 3394-3398.
30. Olas B, Urbańska K, Bryś M. Saponins as modulators of the blood coagulation system and perspectives regarding their use in the prevention of venous thromboembolic incidents. Molecules. 2020; 25(21): 5171. http://dx.doi.org/10.3390/molecules25215171
31. Yang W, Chen X, Li Y, Guo S, Wang Z, Yu X. Advances in pharmacological activities of terpenoids. Nat Prod Commun 2020; 15(3): 1934578X2090355. http://dx.doi.org/10.1177/ 1934578x20903555
32. Mengane SK. Phytochemical Analysis of Adiantum lunulatum. Int J CurrMicrobiolAppl Sci. 2016; 5(11): 351–6. http://dx.doi.org/ 10.20546/ ijcmas.2016.511.040
33. Peter Paul J. Screening of preliminary phytochemicals of Adiantum lunulatum burm. - an important pteridophyte. Screening of preliminary phytochemicals of Adiantum lunulatum burm - an important pteridophyte World Journal of Pharmaceutical Research. 2018; 7.
34. Mukherjee KS, Mondal S, Sohel SMA, Mukherjee P, Chatterjee D, Brahmachari G. A new triterpene from Adiantum lunulatum Burm.ChemInform 2004; 35(6). Available from: http://dx.doi.org/ 10.1002/chin.200406145
35. Brahmachari G, Chatterjee D. Triterpenes from Adiantumlunulactum. Fitoterapia 2002; 73(5): 363–8. Available from: http://dx.doi.org/ 10.1016/s0367-326x(02)00119-3
36. Bhattacharyya K, Kar T, Bocelli G, Righi L, Venkateswarlu Y, Reddy VN. Fern-9 (11)-en-6α-ol-methanol (1/1).ActaCrystallographica Section E: Structure Reports Online. 2001; 57(3): 228–30.
37. Reddy VL, Ravikanth V, Rao TP, Diwan PV, Venkateswarlu Y. A new triterpenoid from the fern Adiantum lunulatum and evaluation of antibacterial activity. Phytochemistry 2001; 56(2): 173–5. Available from: http://dx.doi.org/10.1016/s0031-9422(00)00334-4
38. Rajyalakshmi P, Venkatalaxmi K, Venkatalakshmamma K, Jyothsna Y, Devi KB, Suneetha V. Total carotenoid and beta-carotene contents of forest green leafy vegetables consumed by tribals of south India. Plant Foods Hum Nutr 2001; 56(3): 225–38. Available from: http://dx.doi.org/10.1023/a:1011125232097
39. Manjunatha E, R. Nandeesh, Syed Mansoor Ahmed. Antiulcer and Ulcer Healing Potential of Some Medicinal Plants: A Review. Research Journal of Pharmacognosy and Phytochemistry. 2022; 14(1): 37-2.
40. SamalA.IMPPATRes.in.[cited2022Nov8].Availablefrom:https://cb.imsc.res.in/imppat/phytochemical/Adiantum%20lunulatum.
41. MK. Nithin, G. Veeramani, S. Sivakrishnan. Phytochemical screening and GC-MS Analysis of Rhizome of Drynariaquercifolia. Research J. Pharm. and Tech., 2020; 13(5): 2266-2268.
42. AlfredMaroyi. Evaluation of Pharmacological properties, Phytochemistry and Medicinal uses of Linziaglabra (Asteraceae). Research J. Pharm. and Tech 2021; 14(3): 1741-1746.
43. Moorthy K, Vinodhini R, Senthilkumar B, Punitha T, Senbagam D, Thajuddin N. Phytochemical analysis, in-vitro anti-microbial activity of Indian medicinal ferns Adiantum lunulatum and Hemionitisarifolia. Journal of pharmacy research., 2014; 8(11): 1671–6.
44. Chatterjee A, Khatua S, Acharya K, Sarkar J. A green approach for the synthesis of antimicrobial bio-surfactant silver nanoparticles by using a fern. Dig J NanomaterBiostruct. 2019; 14: 479–90.
45. Dipanjali Devi, RupjyotiGogoi, FarishtaYasmin, KumanandTayung. Antimicrobial activity of Endolichenic fungi isolated from Cryptothecia sp. against some human test pathogens. Research Journal of Pharmacy and Technology. 2022; 15(5): 2193-7.
46. Swathi PP, Harindran J. Evaluation of Hepatoprotective Activity Of Ethanolic Extract Of Adiantum lunulatum Burm F. Evaluation Of Hepatoprotective Activity Of Ethanolic Extract Of Adiantum lunulatum Burm F World Journal of Pharmaceutical Research. 2018; 7(17): 1198–207.
47. Sarkar J, Chakraborty N, Chatterjee A, Bhattacharjee A, Dasgupta D, Acharya K. Green synthesized copper oxide nanoparticles ameliorate defence and antioxidant enzymes in Lens culinaris. Nanomaterials (Basel). 2020; 10(2): 312. http://dx.doi.org/10.3390/nano10020312
48. Prakash S, Ghatuary SK, Prasad S, Parmar M. Extraction, Phytochemical Investigation and Study of Antihyperlipidemic Potential Of Leaves Extract Of Adiantum lunulatum. Extraction, Phytochemical Investigation and Study of Antihyperlipidemic Potential of Leaves Extract of Adiantum lunulatum Asian Journal of Pharmaceutical Education and Research. 2022; 11(3): 135–46.
49. Deshpande MN, Balekar N, Department of Pharmacology, PES’s Rajaram and TarabaiBandekar College of Pharmacy, Farmagudi, Ponda - 403 401, Goa, India. Gastroprotective and ulcer healing activity of ethanolic extract of Adiantum lunulatum. Indian drugs. 2019; 56(03): 68–73. http://dx.doi.org/10.53879/id.56.03.11642
50. Bhatia DK, Pande RK. Antifertility effects of three species of Adiantum ferns decoction in male albino rats. Sharadpauri.org. 2009 [cited 2022 Octc30]. http://jmr.sharadpauri.org/papers/2009/148-156.pdf
51. Marak AD, Mathew B. Traditional Healing Methods for Bone Fracture Practiced by The Garo Tribe of Meghalaya. Plant Archives. 2020; 20(1): 754–8.