Author(s):
K.P. Jaiganesh, T.J. Jasna, A.C. Tangavelou
Email(s):
kpjaiyaganesh@gmail.com
DOI:
10.52711/0975-4385.2021.00028 
Address:
K.P. Jaiganesh1*, T.J. Jasna2, A.C. Tangavelou3
1Division of Pharmacognosy and Phytochemistry Research Laboratory, Dhanalakshmi Srinivasan College of Pharmacy, Perambalur - 621 212, Tamil Nadu, India.
2Department of Pharmacognosy and Phytochemistry, Nehru College of Pharmacy, Pampady, Thiruvilwamala, Thrissur - 680 588, Kerala, India.
3Department of Plant Biology and Plant Biotechnology, Guru Nanak College (Autonomous), Velachery, Chennai 600042, Tamil Nadu, India.
*Corresponding Author
Published In:
Volume - 13,
Issue - 4,
Year - 2021
ABSTRACT:
Hugonia mystax L., (Linaceae), is commonly distributed in the thorny scrubs and tropical dry evergreen forests of Tamil Nadu, which has been valued for centuries in traditional system of medicine for the treatment of various ailments. In the present study was an attempt to investigate the phytochemical nature and anti-inflammatory, antimicrobial potential by adopting suitable methods. Phytochemical analysis of Hugonia mystax L., plant extracts revealed the presence of various biochemical compounds such as alkaloids, flavonoids, glycosides, triterpenoids and saponins etc. Since triterpenoids and flavonoids have remarkable anti-inflammatory activity, so our present work aims at evaluating in vitro anti inflammatory activity of Hugonia mystax L., by HRBC membrane stabilization method. The inhibition of hypotonicity induced HRBC membrane lysis was taken as a measure of the anti-inflammatory activity. The percentage of membrane stabilization for ethanolic extracts and Diclofenac sodium were done at different concentrations. The maximum membrane stabilization of Hugonia mystax L., extracts was found to be 94.97 % at a dose of 2000 µg/ml. Therefore, our studies support the isolation and the use of active constituents from Hugonia mystax L., in treating inflammations.
Cite this article:
K.P. Jaiganesh, T.J. Jasna, A.C. Tangavelou. Phytochemical, In vitro Anti-inflammatory and Antimicrobial Potential of Hugonia mystax L. Research Journal of Pharmacognosy and Phytochemistry. 2021; 13(4):169-3. doi: 10.52711/0975-4385.2021.00028
Cite(Electronic):
K.P. Jaiganesh, T.J. Jasna, A.C. Tangavelou. Phytochemical, In vitro Anti-inflammatory and Antimicrobial Potential of Hugonia mystax L. Research Journal of Pharmacognosy and Phytochemistry. 2021; 13(4):169-3. doi: 10.52711/0975-4385.2021.00028 Available on: https://rjpponline.org/AbstractView.aspx?PID=2021-13-4-2
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