Author(s): Roman Kumar Aneshwari, Amber Vyas, Vishal Jain


DOI: 10.52711/0975-4385.2022.00049   

Address: Roman Kumar Aneshwari, Amber Vyas, Vishal Jain*
University Institute of Pharmacy, Pt. Ravishankar Shukla University, Raipur (C.G.)
*Corresponding Author

Published In:   Volume - 14,      Issue - 4,     Year - 2022

Tephrosia purpurea, which is also termed as sharpunkha in Ayurveda, is a wild herb of family Fabaceae. Geographically it is found at an altitude between 400 m to 1300 m in countries like India, Sri Lanka, China and Australia. Natural habitat of Tephrosia purpurea is in dry, sandy or rocky soil. It is seen growing along the roadside and places where waste are dump. Phytochemical investigations on Tephrosia purpurea shows the presence of constituents such as carbohydrates, protein, amino acid, tannins, saponins, terpenes, flavanones, rotenoids, chalcones, isoflavones, glycosides, alkaloids, flavanols, and sterols. It has also shown the presence of lupeol, lanceolatins A and B semiglabrin, rutin, sitosterol and pongamole. Flavonoids such as (+)-tephrosin A and B, (+)-tephrosone, isoflavone, 7, 4' dihydroxy-3', 5'-dimethoxyflavone and a chalcone, (+)-tephropurpurin were present in the whole plant and that was isolated from it. Different parts of the whole plant has shown variety of pharmacological actions ranging from anti-inflammatory to antitumor along with activities such as antiulcer , hepatoprotective, antioxidant, antimicrobial and antiallergic. Moreover it has also shown insect repellent activity. This review has summarized the literature related to phytochemical and pharmacological study of Tephrosia purpurea (L.) Pers. till August 2012. Tephrosia purpurea is regarded as folk medicine due to several therapeutic properties like anti-daibetic, anticancer, antipyretic. It also has pharmacological importance due to the potent chemical constituent.

Cite this article:
Roman Kumar Aneshwari, Amber Vyas, Vishal Jain. Conspectus on Tephrosia purpurea: An Introduction. Research Journal of Pharmacognosy and Phytochemistry. 2022; 14(4):281-7. doi: 10.52711/0975-4385.2022.00049

Roman Kumar Aneshwari, Amber Vyas, Vishal Jain. Conspectus on Tephrosia purpurea: An Introduction. Research Journal of Pharmacognosy and Phytochemistry. 2022; 14(4):281-7. doi: 10.52711/0975-4385.2022.00049   Available on:

1.    Chaudhari TB, Tambe DA, Chaudhari SR. Phytopharmacology of Tephrosia purpurea Pers. Fabaceae)-A Review, IJPI‟ s Journal of Pharmacognosy and Herbal Formulations. 2012;2(8):1-3.
2.    Chopra RN, Nayar SL. Glossary of Indian medicinal plants. Council of Scientific And Industrial Research; New Delhi; 1956.
3.    Palbag S, Dey BK, Singh NK. Ethnopharmacology, phytochemistry and pharmacology of Tephrosia purpurea. Chinese journal of natural medicines. 2014 Jan 1;12(1):1-7.
4.    Deshpande SS, Shah GB, Parmar NS. Antiulcer activity of Tephrosia purpurea in rats. Indian journal of Pharmacology. 2003 May 1;35(3):168-72.
5.    Sankaran JR. Tefroli in the management of viral hepatitis. Antiseptic. 1980;77(11):643-6.
6.    Kumar A, Dutta M, Bhatt TK, Dalal DS. Use of herbal liver tonic yakrifit in equine practice. Indian veterinary journal. 1997;74(5):424-425.
7.    Gokhale AB, Saraf MN. Tephrosia purpurea: a review of contemporary literature and medicinal properties. INDIAN DRUGS-BOMBAY-. 2000;37(12):553-60.
8.    Pelter A, Ward RS, Rao EV, Raju NR. 8-Substituted flavonoids and 3′-substituted 7-oxygenated chalcones from Tephrosia purpurea. Journal of the Chemical Society, Perkin Transactions 1. 1981:2491-8.
9.    Kumar S, Pandey AK. Chemistry and biological activities of flavonoids: an overview. The Scientific World Journal. 2013;2013.
10.    Badarinath AV, Rao KM, Chetty CM, Ramkanth S, Rajan TV, Gnanaprakash K. A review on in-vitro antioxidant methods: comparisions, correlations and considerations. International Journal of PharmTech Research. 2010 Jan 1;2(2):1276-85.
11.    Pal DI, Verma PR. Flavonoids: A powerful and abundant source of antioxidants. International Journal of Pharmacy and Pharmaceutical Sciences. 2013;5(3):95-8.
12.    Akanksha b. Phytopharmacological uses of tephrosia purpurea-a review. Pharmacophore 2014, 5 (4) : 658-65.
13.    Gitte T and Dhabe A. Anatomical studies on tephrosia purpurea (L.) Pers.- a medicinally important species. International Journal of Institutional Pharmacy and Life Sciences. 2016 june; 6(3): 65-74.
14.    Orwa C, Mutua A, Kindt R, Jamnadass R, Simons A. Psidium Guajava. Agroforestry Database: A Tree Reference and Selection Guide Version. 2009;4.
15.    Babu N, Singh A, Singh R. A review on therapeutic potential and phytochemistry of Tephrosia purpurea. Bulletin of Pure and Applied Sciences-Botany. 2017;36(2):91-104.
16.    Dalwadi PP, Patel JL, Patani PV. Tephrosia purpurea Linn (Sharpunkha, Wild Indigo): a review on phytochemistry and pharmacological studies. Indian Journal of Pharmaceutical and Biological Research. 2014 Jan 1;2(1):108.
17.    Lodhi S, Pawar RS, Jain AP, Singhai AK. Wound healing potential of Tephrosia purpurea (Linn.) Pers. in rats. Journal of Ethnopharmacology. 2006 Nov 24;108(2):204-10.
18.    Sahu TR. Less known uses of weeds as medicinal plants. Ancient science of life. 1984 Apr;3(4):245.
19.    Warrier PK, Nambiar VP. Indian medicinal plants: a compendium of 500 species. Orient Blackswan; 1993.
20.    Sandhya S, Kumar PS, Vinod KR, Banji D, Kumar K. Plants as potent antidiabetic and wound healing agents: A review. Hygeia JD Med. 2011;3(1):11-9.
21.    Venkatanarayana D, Kumar AS, Lakshmi SM. Review on Natural wound healing Agents. Int. J. Phytopharmacy Res. 2010;1(1):1-4.
22.    Billore KV, Yelne MB, Dennis TJ. Database on Medicinal Plants Used in Ayurveda, [M]. Vol. 6, Central Council for Research in Ayurveda and Siddha, India: New Delhi, 2004: 358-373.
23.    Anonymous: Quality Standards of Indian Medicinal Plants[M] Vol 1. Indian Council of Medical Research, India: New Delhi, 2003: 187-197.
24.    Mathews AM, Sujith K, Christina AJ. Muralidharan. Basic Research on the Herb Tephrosia purpurea (l) pers.-the Translational Challenges–A Review. Int J Pharm Chem Sci. 2012;1:466-71.
25.    Kumar VR, Kumar S, Shashidhara S, Anitha S, Manjula M. Comparison of the antioxidant capacity of an important hepatoprotective plants. Int. J. Pharm. Sci. Drug Res. 2011;3(1):48-51.
26.    Murganathan G, Joshi NC, Thabah P, Prakash D. Phytochemical studies and antibacterial activity of Tephrosia purpurea (Linn) root. Biomed. 2007;2(3):305-8.
27.    Gupta DK, Krishnamurti M, Parthasarathi L. Purpurin, a new flavanone from Tephrosia purpurea seeds. Phytochemistry. 1980 Jan 1;19(6):1264.
28.    Sinha B, Natu AA, Nanavati DD. Prenylated flavonoids from Tephrosia purpurea seeds. Phytochemistry. 1982 Jan 1;21(6):1468-70.
29.    Hegazy ME, El-Razek MH, Nagashima F, Asakawa Y, Paré PW. Rare prenylated flavonoids from Tephrosia purpurea. Phytochemistry. 2009 Aug 31;70(11):1474-7.
30.    Chang LC, Chávez D, Song LL, Farnsworth NR, Pezzuto JM, Kinghorn AD. Absolute configuration of novel bioactive flavonoids from Tephrosia purpurea. Organic letters. 2000 Feb 24;2(4):515-8.
31.    Chang LC, Gerhäuser C, Song L, Farnsworth NR, Pezzuto JM, Kinghorn AD. Activity-guided isolation of constituents of Tephrosia purpurea with the potential to induce the phase II enzyme, quinone reductase. Journal of natural products. 1997 Sep 22;60(9):869-73.
32.    Khatri A, Garg A, Agrawal SS. Evaluation of hepatoprotective activity of aerial parts of Tephrosia purpurea L. and stem bark of Tecomella undulata. Journal of ethnopharmacology. 2009 Feb 25;122(1):1-5.
33.    Chinniah A, Mohapatra S, Goswami S, Mahapatra A, Kar SK, Mallavadhani UV, Das PK. On the potential of Tephrosia purpurea as anti-Helicobacter pylori agent. Journal of ethnopharmacology. 2009 Jul 30;124(3):642-5.
34.    Shenoy S, Shwetha K, Prabhu K, Maradi R, Bairy KL, Shanbhag T. Evaluation of antiinflammatory activity of Tephrosia purpurea in rats. Asian Pacific Journal of Tropical Medicine. 2010 Mar 1;3(3):193-5.
35.    Patel A, Patel A, Patel NM. Estimation of Flavonoid, polyphenolic content and in-vitro antioxidant capacity of leaves of Tephrosia purpurea Linn.(Leguminosae). International Journal of Pharma Sciences and Research. 2010 Feb 1;1(1):66-77.
36.    Vishal Gulecha,Thangavel Sivakuma . Anticancer activity of Tephrosia purpurea and Ficus religiosa using MCF 7 cell lines. Asian Pacific Journal of Tropical Medicine (2011)526-529.
37.    Manjula RR, Anand TJ, Sudhir M, Ali SL, Kishore CN. Evaluation of AntiPyretic Activity of Tephrosia purpurea LINN in Albino Rats. American Journal of Phytomedicine and Clinical Therapeutics. 2013 Sep 30;1(6):467-70.
38.    Hussain T, Fareed S, Siddiqui HH, Vijaykumar M, Rao CV. Acute and subacute oral toxicity evaluation of Tephrosia purpurea extract in rodents. Asian Pacific journal of tropical disease. 2012 Apr 1;2(2):129-32.
39.    Janbaz KH, Qadir MI, Jan A, Gilani AH. Anti-diarrheal activity of methanolic extract of Tephrosia purpurea. Acta. Pol. Pharm. 2013 Mar 1;79(2):345-7.
40.    Janbaz KH, Jan A, Qadir MI, Gilani AH. Spasmolytic, bronchodilator and vasorelaxant activity of methanolic extract of Tephrosia purpurea. Acta. Pol. Pharm. 2013 Mar 1;79(2):261-9.
41.    Jain A, Nahata A, Singhai AK. Effect of Tephrosia purpurea (L.) pers. Leaves on gentamicin-induced nephrotoxicity in rats. Scientia pharmaceutica. 2013 Jul 22;81(4):1071-88.
42.    Muthukrishnan S, Krishnamoorthy SM. International Journal of Pharmaceutical Development and technology. phytochemical and antimicrobial profile of tephrosia purpurea. International Journal of Pharmaceutical Development and Technology. 2014 ; 4 (4): 267-270.
43.    Ajitha B, Reddy YA, Reddy PS. Biogenic nano-scale silver particles by Tephrosia purpurea leaf extract and their inborn antimicrobial activity. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 2014 Mar 5;121:164-72.
44.    Gayathri Devi S, Sabna KA, Mary Shoba Das C. Evaluation of in vitro free radical scavenging activity of Tephrosia purpurea. World journal of Pharmacy and Pharmaceutical science. 2014 May 7;3(7):1236-44.
45.    Gora RH, Baxla SL, Kerketta P, Patnaik S, Roy BK. Hepatoprotective activity of Tephrosia purpurea against arsenic induced toxicity in rats. Indian journal of pharmacology. 2014 Mar;46(2):197.
46.    Bhadada SV, Goyal RK. Effect of aqueous extract of Tephrosia purpurea on cardiovascular complications and cataract associated with streptozotocin-induced diabetes in rats. Indian journal of pharmaceutical sciences. 2015 Sep;77(5):522.
47.    Lodhi S, Jain A, Jain AP, Pawar RS, Singhai AK. Effects of flavonoids from Martynia annua and Tephrosia purpurea on cutaneous wound healing. Avicenna journal of phytomedicine. 2016 Sep;6(5):578.
48.    Anbarasi A, Vidhya R. Evaluation of in vitro anti-inflammatory activity of Tephrosia purpurea (Seed). Asian Journal of Pharmaceutical Research. 2015;5(2):83-9.
49.    Pandey MM, Khatoon S, Rastogi S, Rawat AK. Determination of flavonoids, polyphenols and antioxidant activity of Tephrosia purpurea: a seasonal study. Journal of integrative medicine. 2016 Nov 1;14(6):447-55.
50.    Bhadada SV, Goyal RK. Effect of flavonoid rich fraction of Tephrosia purpurea (Linn.) Pers. on complications associated with streptozotocin-induced type I diabetes mellitus. Indian journal of experimental biology.2016 July; 54:457-466.
51.    Padmapriya R, Ashwini S, Raveendran R. In vitro antioxidant and cytotoxic potential of different parts of Tephrosia purpurea. Research in pharmaceutical sciences. 2017 Feb;12(1):31.
52.    Padmapriya R, Gayathri L, Ronsard L, Akbarsha MA, Raveendran R. In vitro anti-proliferative effect of tephrosia purpurea on human hepatocellular carcinoma cells. Pharmacognosy magazine. 2017 Jan;13(Suppl 1):S16.
53.    Shukla A, Mourya P. Investigations for anti-urolithiatic activity of roots against Tephrosia purpurea ethylene glycol-induced renal calculi in rats. Asian Journal of Pharmacy and Pharmacology. 2016;2(2):40-3.
54.    Bhadada SV, Vyas VK, Goyal RK. Protective effect of Tephrosia purpurea in diabetic cataract through aldose reductase inhibitory activity. Biomedicine and Pharmacotherapy. 2016 Oct 1;83:221-8.
55.    Atul Kumar Gangwar, Ashoke K. Ghosh. Anti inflammatory activity of Methanolic stem extract of Tephrosia purpurea. Sch. Acad. J. Pharm., 2016; 5(4): 92-94.
56.    Krishna NM, Chowdary KA. Evaluation of anticonvulsant activity of stem bark extract of Tephrosia purpurea. Indian Journal of Research in Pharmacy and Biotechnology. 2017;5(3):173-6.
57.    Verma N, Singh J. Evaluation of hepatoprotective activity of tephrosia purpurea linn. Stem. International Educational Applied Scientific Research Journal. 2017 Jul 13;2(7).
58.    Krishna NM, Chowdary KA. Evaluation of nephroprotective activity ethanolic extract of stem bark extract of Tephrosia purpurea. Indian Journal of Research in Pharmacy and Biotechnology. 2017;5(3):177-85.
59.    Laishram A, Naik J, Reddy S, Jayasimha Rayalu D. Phytochemical analysis, TLC profiling and antimicrobial activity of Tephrosia purpurea. International Journal of Pharmacy and Life Sciences. 2013 Feb 1;4(2).
60.    Sharma P, Rastogi S, Bhatnagar S, Srivastava JK, Dube A, Guru PY, Kulshrestha DK, Mehrotra BN, Dhawan BN. Antileishmanial action of Tephrosia purpurea linn, extract and its fractions against experimental visceral leishmaniasis. Drug development research. 2003 Dec 1;60(4):285-93.
61.    Dabur R, Gupta A, Mandal TK, Singh DD, Bajpai V, Gurav AM, Lavekar GS. Antimicrobial activity of some Indian medicinal plants. African Journal of Traditional, Complementary and Alternative Medicines. 2007;4(3):313-8.
62.    Damre AS, Gokhale AB, Phadke AS, Kulkarni KR, Saraf MN. Studies on the immunomodulatory activity of flavonoidal fraction of Tephrosia purpurea. Fitoterapia. 2003 Apr 1;74(3):257-61.
63.    Kavitha K, Manoharan S. Anticarcinogenic and antilipidperoxidative effects of Tephrosia purpurea (Linn.) Pers. in 7, 12-dimethylbenz (a) anthracene (DMBA) induced hamster buccal pouch carcinoma. Indian journal of pharmacology. 2006 May 1;38(3):185.
64.    Vijayakumar P, Thirumurugan V, Bharathi K, Surya S, Kavitha M, Muruganandam G, Saraswathy N, Sethuraman M. An Evaluation of Anti Diabetic Potential and Physico-Phytochemical Properties of Tephrosia purpurea (Linn.) Pers in Streptozotocin Induced Diabetes Model in Albino Rats. Int. J. Pharm. Sci. Rev. Res. 2014;24(1):46-50.
65.    Kumar AS, Amudha P, Kannan CS. Evaluation of anxiolytic activity of hydroalcoholic activity of Tephrosia purpuria (L) PERS on swiss albino mice. International Journal of Pharmaceutical Sciences and research. 2011 May 1;2(5):1262.
66.    Junapudi S, Krishna JY, Chari PV, Rao GE, MM C, Rao P. Evaluation of Antiarthritic Activity of Ethanolic Extract of Tephrosia purpurea (Linn.). Inventi Rapid: Ethnopharmacology. 2013 Aug 24.
67.    Mujeeb MO, Zafar R, Husain AS, Ahmad AF. Antihepatotoxic activity of aqueous extracts of callus culture of Tephrosia purpurea (L) pers. Acta Pol Pharmac Drug Res. 2012 May 1;69:545-9.
68.    Giri S. Analgesic and antimicrobial effect of methanolic extract of Tephrosia purpurea root bark.  International Journal of Academic Research and Development .  March 2018; Page No. 689-690.
69.    Jain A, Singhai AK. Effect of Tephrosia Purpurea Pers on gentamicin model of acute renal failure. In13th International Conference on Biomedical Engineering 2009 (pp. 1438-1442). Springer, Berlin, Heidelberg.
70.    Gora RH, Kerketta P, Baxla SL, Toppo R, Prasad R, Patra PH, Roy BK. Ameliorative effect of Tephrosia purpurea in arsenic-induced nephrotoxicity in rats. Toxicology international. 2014 Jan;21(1):78.
71.    Mukherjee PK. Quality control of herbal drugs [M]. India: New Delhi, Business Horizon Publishers, 2002: 02-03.

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