Epiphyllum oxypetalum: Unveiling the Medicinal Potential of The Queen of The Night

Rutuja Kamble; Pushpalata Sherekar

doi:10.52711/0975-4385.2025.00022

Research Journal of Pharmacognosy and Phytochemistry

ISSN

0975-4385 (Online)
0975-2331 (Print)

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Epiphyllum oxypetalum: Unveiling the Medicinal Potential of The Queen of The Night

Author(s): Rutuja Kamble, Pushpalata Sherekar

Email(s): rutujakamble681@gmail.com

DOI: 10.52711/0975-4385.2025.00022

Address: Rutuja Kamble1, Pushpalata Sherekar2
Department of Pharmacognosy, Shivaji University, Kolhapur, Maharashtra, India.
Ashokrao Mane College of Pharmacy, Peth - Vadgaon.
*Corresponding Author

Published In: Volume - 17, Issue - 2, Year - 2025

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ABSTRACT:
Epiphyllum oxypetalum is a wide remedial plant that has a put to the cactus circle of relatives. it's continuously called the Ruler of the night time, night time Growing Cereus, or woman of the night due to its astonishing closeness to the Lotus and the reality that, like most noteworthy white leafage, it grows at night. in extension to the doubtlessly unmistakable and bitty evaluation, the physicochemical and phytochemical places of the powdered takes off had been reviewed. The smoothly going on bioactive mixes interior the takes off have been surveyed the operation of a grouping of dissolvable extricates. Proteins, carbohydrates, sterols, flavonoids, alkaloids, phenols, tannins, and saponins were each show, in line with the bits of knowledge. Physicochemical evaluation, which secured mishap on drying, searing flotsam and jetsam values, water dissolvability, destructive insolubility, and pH, made a contrast in identity and awesome control. anti-most cancers, antioxidant, antibacterial, and against urolithiasis conduct are among its multitudinous pharmacological characteristics.

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Cite this article:
Rutuja Kamble, Pushpalata Sherekar. Epiphyllum oxypetalum: Unveiling the Medicinal Potential of The Queen of The Night. Research Journal of Pharmacognosy and Phytochemistry. 2025; 17(2):130-4. doi: 10.52711/0975-4385.2025.00022

Cite(Electronic):
Rutuja Kamble, Pushpalata Sherekar. Epiphyllum oxypetalum: Unveiling the Medicinal Potential of The Queen of The Night. Research Journal of Pharmacognosy and Phytochemistry. 2025; 17(2):130-4. doi: 10.52711/0975-4385.2025.00022 Available on: https://rjpponline.org/AbstractView.aspx?PID=2025-17-2-9

REFERENCE:
1.    Devi KS, Narayana SL, Menghani P, George Kutty J. Microscopic, pharmacogenetic and phytochemical screening of Epiphyllum oxypetalum (dc) haw leaves. Journal of Pharmacognosy and Phytochemistry. 2018; 7(6): 972-80.
2.    Upendra RS, Khandelwal P. Assessment of nutritive values, phytochemical constituents and biotherapeutic potentials of Epiphyllum oxypetalum. International Journal of Pharmacy and Pharmaceutical Science. 2012; 4(5): 421-5.
3.    Dandekar R, Fegade B, Bhaskar VH. GC-MS analysis of phytoconstituents in alcohol extract of Epiphyllum oxypetalum leaves. Journal of Pharmacognosy and Phytochemistry. 2015; 4(1): 148-54.
4.    Jayashree P, Shalini M, Meenambiga SS, Suganya V. Phytochemical Screening and GC-MS Analysis of Epiphyllum oxypetalum flower extracts. Research Journal of Pharmacy and Technology. 2020; 13(12): 5893-7.
5.    Emembolu LN, Onukwuli OD, Okafor VN. Characterization and optimization study of Epiphyllum oxypetalum extract as corrosion inhibitor for mild steel in 3 M H2SO4 solutions. World Scientific News. 2020;145:256-73.
6.    Adhikary K. Pentas Lanceolata and Epiphyllum Oxypetalum: Ornamental Plants with Medicinal Value-A Mini Review. Editorial Board. 2020 Jun; 9(6).
7.    Ingale S, Sajid MM. Comparative study of proximate composition of stem and leaves of epiphyllum oxypetalum from different district of Maharashtra. World Journal of Pharmaceutical Research. 2016 Feb; 5(3): 790-9.
8.    Ojatula AO, Idowu MO, Akinsowon RO. Chemical Composition Profiling of Epiphyllum oxypetalum (DC.) Haw. (Queen of the Night) Grown in Akure Metropoly, Ondo State, Nigeria. Rivers State University Journal of Biology and Applied Sciences. 2022; 2(2).
9.    Ortiz TA, Moritz A, de Oliveira MA, Lone AB, Nakatani SH, Takahashi LS. Optimal conditions for germination of seeds of Epiphyllum oxypetalum. African J Agric Res. 2014 Sep 10; 9(34): 2630-7.
10.    Morris C. Painting colonial plants: epiphyllum species and hybrids. Australian Garden History. 2007 May 1; 18(5): 6-9.
11.    Vanitha S, Prakash GA, Malarvizhi M, Periyamal K, Shekhar AP. Treatment of Effluents from Jewellery Industries by using Activated Carbons Prepared from Epiphyllum Oxypetalum (Cactace) Wastes. J. Environ. Nanotechnol. 2014; 3(2): 122-9.
12.    Kimnach M. Some succulent memories. Cactus and Succulent Journal. 2008 May; 80(3): 134-9.
13.    http://en.wikipedia.org/wiki/Epiphyllum_oxypetalum.
14.    R. Abhishek Biswal, P. Jayashree, K. Mirunaalini, and V. Pazhamalai. Molecular docking studies of bioactive compounds from the leaf extract of Epiphyllum oxypetalum against Treponema pallidum, Zika virus, and liver cirrhosis, J. Appl. Pharm. Sci. 2019; 9(11): 69–77 doi:10.7324/JAPS.2019.91109[2]
15.    L. P. Dwita, F. Hasanah, R. Srirustami, R. Purnomo, and S. Harsodjo. Wound healing properties of Epiphyllum oxypetalum (DC.) Haw. leaf extract in streptozotocin–induced diabetic mice by topical application, Wound Med. 2019; 26(1): 100-160.
16.    F. B. R. Dandekar, and V. H. Bhaskar. GC–MS Analysis of phytoconstituents in alcohol extract of Epiphyllum oxypetalum extract. J. Pharmacogn. Phytochem. 2015; 4: 149–154 Doi: 10.7324/JAPS.2019.91109
17.    Theertha M, Rani M. In-Vitro Anti-Diabetic Studies and In-Vitro Anti-Inflammatory Activity in an Underutilised Plant Epiphyllum oxypetalum (DC) Hawthorn Leaves.
18.    Mahmad A, Ubaidah T, Salim F, Shaharun MS. Screening the in vitro Antimicrobial and Antioxidant Activities of Methanolic Extract of Epiphyllum oxypetalum (DC) Haw. Leaf. Current Science and Technology. 2022 Dec 30; 2(1): 40-7.
19.    A. Mahmad, M. S. Shaharun, B. Saad and G. K. Dash, Epiphyllum oxypetalum haw.: a lesser-known medicinal plant. Indo Am. J. Pharm. 2017; 4(10):3670.3672 doi:10.5281/zenodo.1036005.
20.    Mahmad A, Ubaidah T, Salim F, Shaharun MS. Screening the in vitro Antimicrobial and Antioxidant Activities of Methanolic Extract of Epiphyllum oxypetalum (DC.) Haw. Leaf. Current Science and Technology. 2022 Dec 30; 2(1): 40-7.
21.    K. R. Sunaja Devi, S. L. Narayana, M. Palak and G. Josna. Microscopic, pharmacognostic and phytochemical screening of Epiphyllum oxypetalum (dc) haw leaf extract. J. Pharmacogn. Phytochem. 2018; 7(6): 972–980.
22.    Pore AV, Bais SK, Kazi SM, Nikte AA. Assessment of in-anti urolithiatic activity epiphyllum oxypetalum. International Journal of Pharmacy and Herbal Technology. 2023; 1(2): 72-6.
23.    Sheeba Rani MA. In-Vitro Anti-Diabetic Studies and In-Vitro Anti-Inflammatory Activity in an Underutilised Plant Epiphyllum oxypetalum (DC.) Hawthorn Leaves. Bulletin of Pure & Applied Sciences-Botany. 2021 Jan 1(1).
24.    Naik SA, Naikwade ns. Anticancer activity of epiphyllum oxypetalum (DC.) Leaves extract by in-vivo in-vitro models. IJPSR. 2021; 12(8): 4229-4239.
25.    Bammou M, Elbouny H, El Finou H, Ouahzizi B, Sellam K, Nassiri L, Alem C, El Rhaffari L, Bouhlali ED. Ethnobotanical survey of medicinal plants claimed by traditional herbal practitioners to manage digestive disorders in an oasis of Tafila let-Morocco. Plant Science Today. 2024 Mar 30; 11(sp1).
26.    Sheeba Rani MA. In-Vitro Anti-Diabetic Studies and In-Vitro Anti-Inflammatory Activity in an Underutilised Plant Epiphyllum oxypetalum (DC.) Hawthorn Leaves. Bulletin of Pure & Applied Sciences-Botany. 2021 Jan 1(1).
27.    Zhang Y, Zhang Y, Tian Q, Wei L, Zhu T, Zhou Z, Wang J, Liu Z, Tang W, Xiao H, Liu M. Floral scent emission of Epiphyllum oxypetalum: identification of a novel cytosol-localized geraniol biosynthesis pathway. bioRxiv. 2023 Nov 26: 2023-11.
28.    Ma QY, Xu QD, Chen N, Zeng WC. A polysaccharide from Epiphyllum oxypetalum (DC.) Haw. and its immunomodulatory activity. International Journal of Biological Macromolecules. 2023 Dec 31; 253:126792.
29.    Dwita LP, Hasanah F, Srirustami R, Purnomo R, Harsodjo S. Wound healing properties of Epiphyllum oxypetalum (DC.) Haw. leaf extract in streptozotocin-induced diabetic mice by topical application. Wound Medicine. 2019 Sep 1; 26(1): 100160.

1.    Devi KS, Narayana SL, Menghani P, George Kutty J. Microscopic, pharmacogenetic and phytochemical screening of Epiphyllum oxypetalum (dc) haw leaves. Journal of Pharmacognosy and Phytochemistry. 2018; 7(6): 972-80.
2.    Upendra RS, Khandelwal P. Assessment of nutritive values, phytochemical constituents and biotherapeutic potentials of Epiphyllum oxypetalum. International Journal of Pharmacy and Pharmaceutical Science. 2012; 4(5): 421-5.
3.    Dandekar R, Fegade B, Bhaskar VH. GC-MS analysis of phytoconstituents in alcohol extract of Epiphyllum oxypetalum leaves. Journal of Pharmacognosy and Phytochemistry. 2015; 4(1): 148-54.
4.    Jayashree P, Shalini M, Meenambiga SS, Suganya V. Phytochemical Screening and GC-MS Analysis of Epiphyllum oxypetalum flower extracts. Research Journal of Pharmacy and Technology. 2020; 13(12): 5893-7.
5.    Emembolu LN, Onukwuli OD, Okafor VN. Characterization and optimization study of Epiphyllum oxypetalum extract as corrosion inhibitor for mild steel in 3 M H2SO4 solutions. World Scientific News. 2020;145:256-73.
6.    Adhikary K. Pentas Lanceolata and Epiphyllum Oxypetalum: Ornamental Plants with Medicinal Value-A Mini Review. Editorial Board. 2020 Jun; 9(6).
7.    Ingale S, Sajid MM. Comparative study of proximate composition of stem and leaves of epiphyllum oxypetalum from different district of Maharashtra. World Journal of Pharmaceutical Research. 2016 Feb; 5(3): 790-9.
8.    Ojatula AO, Idowu MO, Akinsowon RO. Chemical Composition Profiling of Epiphyllum oxypetalum (DC.) Haw. (Queen of the Night) Grown in Akure Metropoly, Ondo State, Nigeria. Rivers State University Journal of Biology and Applied Sciences. 2022; 2(2).
9.    Ortiz TA, Moritz A, de Oliveira MA, Lone AB, Nakatani SH, Takahashi LS. Optimal conditions for germination of seeds of Epiphyllum oxypetalum. African J Agric Res. 2014 Sep 10; 9(34): 2630-7.
10.    Morris C. Painting colonial plants: epiphyllum species and hybrids. Australian Garden History. 2007 May 1; 18(5): 6-9.
11.    Vanitha S, Prakash GA, Malarvizhi M, Periyamal K, Shekhar AP. Treatment of Effluents from Jewellery Industries by using Activated Carbons Prepared from Epiphyllum Oxypetalum (Cactace) Wastes. J. Environ. Nanotechnol. 2014; 3(2): 122-9.
12.    Kimnach M. Some succulent memories. Cactus and Succulent Journal. 2008 May; 80(3): 134-9.
13.    http://en.wikipedia.org/wiki/Epiphyllum_oxypetalum.
14.    R. Abhishek Biswal, P. Jayashree, K. Mirunaalini, and V. Pazhamalai. Molecular docking studies of bioactive compounds from the leaf extract of Epiphyllum oxypetalum against Treponema pallidum, Zika virus, and liver cirrhosis, J. Appl. Pharm. Sci. 2019; 9(11): 69–77 doi:10.7324/JAPS.2019.91109[2]
15.    L. P. Dwita, F. Hasanah, R. Srirustami, R. Purnomo, and S. Harsodjo. Wound healing properties of Epiphyllum oxypetalum (DC.) Haw. leaf extract in streptozotocin–induced diabetic mice by topical application, Wound Med. 2019; 26(1): 100-160.
16.    F. B. R. Dandekar, and V. H. Bhaskar. GC–MS Analysis of phytoconstituents in alcohol extract of Epiphyllum oxypetalum extract. J. Pharmacogn. Phytochem. 2015; 4: 149–154 Doi: 10.7324/JAPS.2019.91109
17.    Theertha M, Rani M. In-Vitro Anti-Diabetic Studies and In-Vitro Anti-Inflammatory Activity in an Underutilised Plant Epiphyllum oxypetalum (DC) Hawthorn Leaves.
18.    Mahmad A, Ubaidah T, Salim F, Shaharun MS. Screening the in vitro Antimicrobial and Antioxidant Activities of Methanolic Extract of Epiphyllum oxypetalum (DC) Haw. Leaf. Current Science and Technology. 2022 Dec 30; 2(1): 40-7.
19.    A. Mahmad, M. S. Shaharun, B. Saad and G. K. Dash, Epiphyllum oxypetalum haw.: a lesser-known medicinal plant. Indo Am. J. Pharm. 2017; 4(10):3670.3672 doi:10.5281/zenodo.1036005.
20.    Mahmad A, Ubaidah T, Salim F, Shaharun MS. Screening the in vitro Antimicrobial and Antioxidant Activities of Methanolic Extract of Epiphyllum oxypetalum (DC.) Haw. Leaf. Current Science and Technology. 2022 Dec 30; 2(1): 40-7.
21.    K. R. Sunaja Devi, S. L. Narayana, M. Palak and G. Josna. Microscopic, pharmacognostic and phytochemical screening of Epiphyllum oxypetalum (dc) haw leaf extract. J. Pharmacogn. Phytochem. 2018; 7(6): 972–980.
22.    Pore AV, Bais SK, Kazi SM, Nikte AA. Assessment of in-anti urolithiatic activity epiphyllum oxypetalum. International Journal of Pharmacy and Herbal Technology. 2023; 1(2): 72-6.
23.    Sheeba Rani MA. In-Vitro Anti-Diabetic Studies and In-Vitro Anti-Inflammatory Activity in an Underutilised Plant Epiphyllum oxypetalum (DC.) Hawthorn Leaves. Bulletin of Pure & Applied Sciences-Botany. 2021 Jan 1(1).
24.    Naik SA, Naikwade ns. Anticancer activity of epiphyllum oxypetalum (DC.) Leaves extract by in-vivo in-vitro models. IJPSR. 2021; 12(8): 4229-4239.
25.    Bammou M, Elbouny H, El Finou H, Ouahzizi B, Sellam K, Nassiri L, Alem C, El Rhaffari L, Bouhlali ED. Ethnobotanical survey of medicinal plants claimed by traditional herbal practitioners to manage digestive disorders in an oasis of Tafila let-Morocco. Plant Science Today. 2024 Mar 30; 11(sp1).
26.    Sheeba Rani MA. In-Vitro Anti-Diabetic Studies and In-Vitro Anti-Inflammatory Activity in an Underutilised Plant Epiphyllum oxypetalum (DC.) Hawthorn Leaves. Bulletin of Pure & Applied Sciences-Botany. 2021 Jan 1(1).
27.    Zhang Y, Zhang Y, Tian Q, Wei L, Zhu T, Zhou Z, Wang J, Liu Z, Tang W, Xiao H, Liu M. Floral scent emission of Epiphyllum oxypetalum: identification of a novel cytosol-localized geraniol biosynthesis pathway. bioRxiv. 2023 Nov 26: 2023-11.
28.    Ma QY, Xu QD, Chen N, Zeng WC. A polysaccharide from Epiphyllum oxypetalum (DC.) Haw. and its immunomodulatory activity. International Journal of Biological Macromolecules. 2023 Dec 31; 253:126792.
29.    Dwita LP, Hasanah F, Srirustami R, Purnomo R, Harsodjo S. Wound healing properties of Epiphyllum oxypetalum (DC.) Haw. leaf extract in streptozotocin-induced diabetic mice by topical application. Wound Medicine. 2019 Sep 1; 26(1): 100160.