Sea Weed Therapy: Medicinal and Cosmeceutical Value, A Review
Kamble M.A.*, Dhabarde D.M., Sant
A.P., Ingole A.R., Potnis
V.V.
Kamla Nehru College of Pharmacy, Butibori, Nagpur
-441108 (M.S.)
ABSTRACT:
Seaweeds
are marine algae having unique structure and biochemical composition. It can be
used highly for its multi-functional properties in the form of food, energy, medicine
and cosmetics. Many metabolites isolated from these marine algae have been
shown to possess bioactive efforts. Among the different compounds with
functional properties, antioxidants are the most widely studied. Moreover, the
important role of antioxidants in human health has been demonstrated, thus
increasing the interest in such products and their demand by consumers. Marine
algae serve as important resources for bioactive natural products. Seaweeds are
a good source of antimicrobial compounds, antioxidants and other bioactive
compounds. There is an interest to utilize these products as nutraceuticals and in functional foods. Compounds with cytostatic, antiviral, anthelmintic,
antifungal and antibacterial activities have been detected in green, brown and
red algae. Considering their great taxonomic diversity, investigations related
to the search of new biologically active compounds from algae can be seen as
almost unlimited field. In the domain of beauty and cosmetology, surprisingly
beneficial results have been seen in certain treatments with seaweed, in case
of falling hair, dandruff, acne skin eruption, cellulitis,
slimming and rejuvenation of skin. The beneficial properties in the sphere of
modern medicinal culture, is not only in the achievement of cures, but also in
the fact that, being a natural herbal therapy, the harmful effect of modern day
drugs can be eliminated. Seaweed contains all the active elements found in the
live cells, like nitrogen, phosphorus, sulphur,
calcium, potassium, magnesium etc. Certain elements in seaweed allow the skin
to assimilate phosphorus and calcium, which stimulate the skin cells. Seaweed
is effectively used in the treatment of the rejuvenation of cells and tissue,
broken nails, cellulitis, dermatosis,
acne falling hairs, beauty mask etc.
KEYWORDS: Seaweeds,
Thalassotherapy, Antioxidents,
Nutraceuticals, Cosmetics.
INTRODUCTION:
Seaweeds
constitute a source of non-phytoplankton production; provide energy for
associated grazers and contribute remarkably to the benthic detritus food
chains. From an ecological perspective, seaweeds are providers of the
structural integrity of many biotopes especially low energy shores where they
are predominant in terms of size and occupiers of space. Seaweed
Therapy (or Thalassotherapy) is very popular with
arthritis, osteo-arthritis and rheumatoid sufferers,
people with Eczema and soriasis, hard working manual
labors, gardeners, craftsmen and women, with stiff sore muscles and joints.
Recently
the conventional cosmetic industry is shifting its focus from merely the beauty
culture to the value addition of cosmetics. These newer cosmetics are better cosmaceuticals wherein a few claims are made regarding its
health enhancing properties.
Marine macro algae, or
seaweeds, are plant-like organisms that generally live attached to rock or
other hard substrata in coastal areas. Macro algae can be classified as red
algae (Rhodophyta), brown algae (Phaeophyta)
or green algae (Chlorophyta) depending on their
nutrient and chemical composition. Seaweeds serve as an important source of
bioactive natural substances. Red and brown algae are almost exclusively
marine, whilst green algae are also common in freshwater (rivers and lakes),
and even in terrestrial (rocks, walls, houses, and tree bark in damp places)
situations.
The
red color of these algae results from the pigments phycoerythrin
and phycocyanin. This masks the other pigments,
Chlorophyll a (no Chlorophyll b), beta-carotene and a number of unique
xanthophylls.
Examples of
Chlorophyta (Green Algae) are Chlorella,
Chlamydomonas, Spirogyra, Ulva. Green seaweeds. Green
color is due to chlorophyll a and b which are present in the same
proportions, beta-carotene (a yellow pigment), as well as various
characteristic xanthophylls (yellowish or brownish pigments).
Medicinal value of seaweed:
Brown
seaweed: Brown algal preparations have been used as detoxifying agents.1,2
The iodine and other elements in the seaweeds inhibit absorption of similar
radioactive elements by the body. In addition, there is some chelation of contaminants such as Strontium 90 by alginates
in seaweeds. More recently, it has been demonstrated that Undaria
ingestion assists in eliminating dioxins in rats.3
Antiviral Effects:
Brown
seaweeds, including the commonly eaten Undaria,
have inhibitory effects on herpes viruses. Herpes viruses are important human
pathogens and include Herpes simplex (HSVI), genital herpes (HSVII), Varicella/chicken pox/shingles, cytomegalovirus,
Epstein-Barr virus (EBV), herpes6,7 (Roseola,
post-transplant infections), and herpes8 (associated with Kaposis
sarcoma). In Japan, where ingestion of brown seaweed in the diet averages 23 g
per day with a high of 12 g calculated as dry weight,4 there is a
lower rate of reactivation of HSVI,5 and the lowest levels of HSVII
compared to other countries.6
Anticancer Effects:
Researchers
have found that dietary brown algae and their extracts inhibit carcinogen-
induced breast cancers, lung metastases, and leukemia in animal models.6-12
Similarly, tests on the seaweed extracts in bacterial systems revealed that the
extracts had a profound antimutagenic quality.13,14
Table 1. The seaweed: Classes of marine
algae Examples of edible seaweed Latin binomials
Class of seaweed |
Examples of edible seaweed |
Latin bionomials |
Brown |
Wakame; mekabu kelp or kombu |
Undaria pinnatifida Laminaria species |
Red |
Nori (Japan)
or Laver bread
(Wales) |
Porphyra species |
Green |
Sea lettuce |
Ulva and Enteromorpha species |
Effects on Immunity and Inflammation:
Stimulation
of T-cell multiplication in-vitro by seaweed extracts15, 16 may
account for in vivo observations by other researchers, including increased monocytes in cattle that were fed seaweed-extract sprayed
grasses.17The extensive gut lymph tissue would contact seaweeds
passing through the gut. Specialized T cells in gut lymphatic tissue are
important in achieving a rapid response to pathogens, in particular, to viruses
such as HSVI18,19 and may also modulate intestinal lipid metabolism.20
Inflammatory disorders, such as psoriasis and some types of colitis, are
characterized by an excessive presence of leukocytes and may be ameliorated by
seaweed ingestion. Algal-derived fucoidans inhibit
the passage of leucocytes into tissues by receptor blocking. These fucoidans are being investigated clinically for their
potential to prevent destruction of postischemic
heart muscle by invading leucocytes.21
Effects on Plasma Cholesterol and Hypertension
Many
foods are known to reduce cholesterol levels and brown algae fall into this
category. Undaria ingestion results in
lower cholesterol levels in rats.22This effect on lipid processing
seems to be the result of stimulation of liver enzymes.23
Antioxidant activity:
Antioxidant compounds play an
important role against various diseases (e.g., chronic inflammation, atherosclerosis,
cancer and cardiovascular disorders) and ageing processes, which explains their
considerable commercial potential in medicine, and the cosmetic industry.
Moreover, interest in employing antioxidants from natural sources is
considerably enhanced by consumer preference for natural products and concern
about the potential toxic effects of synthetic antioxidants
Antimicrobial properties:
Seaweeds are considered a source
of bioactive compounds as they are able to produce a
great variety of
secondary metabolites characterized by a broad spectrum of
biological activities. Although seaweeds grow in a harsh
environment, they seldom suffer any serious photodynamic damage during metabolism. This fact implies that seaweed cells
have some protective compounds and
mechanisms. Since seaweeds are a good source
of antimicrobial compounds, ω3
fatty acids, antioxidants and other bioactive compounds,
there is an interest to utilize these products as nutraceuticals and in functional foods. Compounds,
such
as polyphenols,
flavonoids and polysaccharides, having
antioxidant and antimicrobial
activities have been detected
in brown, red and
green algae.24
Mineral Contents:
Seaweed contains all the active
elements found in the live cells, like nitrogen, phosphorus, sulphur, calcium, potassium, magnesium etc. Certain
elements in seaweed allow the skin to assimilate phosphorus and calcium, which
stimulate the skin cells.
Cosmeceutical use of seaweed.
·
Magnesium - works with calcium and potassium to balance cells, metabolises Vitamin C and calcium, soothes nerves, helps to
convert blood sugar into energy, is essential for nerve and muscle function.
· Potassium - regulates
fluid in the body, maintains alkalinity and correct mineral balance and
composition of cell fluid, converts glucose to muscle energy, active in enzyme
reactions and formation of protein, and essential for nerve and muscle function.
·
Iodine - boosts metabolism and an essential ingredient of
hormones, particularly in the thyroid.
·
Sulphur - an essential component of protein,
Vitamin B1 and biotin, required for healthy nails, hair and skin.
·
Bromine - passes into the bloodstream through the skin, and works
on the nervous system, calming and relaxing nerves.
Table 2: Nutritive values of some
seaweed species (in %)
Class of seaweeds |
Protein |
Lipid |
Carbohydrates |
Ash |
|
Ulva |
26.1 |
2.1 |
42 |
7.8 |
|
Enteromorpha |
19.5 |
0.3 |
64.9 |
15.2 |
|
Monostroma |
20 |
1.2 |
63.9 |
14.9 |
|
Laminaria |
16.1 |
2.4 |
39.3 |
19.6 |
|
Alaria |
17.1 |
3.6 |
39.8 |
14.9 |
|
Sargassum |
19 |
2.9 |
33 |
16.2 |
|
Padina |
18.81 |
1.7 |
31.6 |
10.3 |
|
The skin which has been well
nourished, free of toxins, well balanced and well mineralized, does not suffer
any problem and is in a good condition to resist elements which could not
attack it. The action of seaweed on certain bacterial diseases (acne) is
spectacular. On the other hand the chlorophyll contains helps photosynthesis,
which helps to nourish the cell. This advantage can be seen in the effect of
seaweed beauty masks25.
Advantages:
·
Achieves the skin balance by rehydrating the epidermis.
·
Provides the necessary minerals salts, amino acids, vitamins A B C
D and E.
·
Penetrate the skin by osmosis.
·
Makes the skin supple, soft, smooth, and firm.
·
Suits all types of skins.
·
Closes open pores.
·
Tone up the flabby tissues and has a remarkable on wrinkles of the
neck and under eye bags.
·
Clear up dark spots by achieving an equilibrium in the oily skin
and other problems. And has an effect on the life of epidermis and helps to
conserve it.
Acne usually appears when there
is a change in hormonal activity, usually occurs on seborrhic
skin, because the sebaceous glands are stimulated by male hormones. Blackheads
forms due to grease accumulating in a pores and oxidation of the head. To cure
acne the hyperactivity of sebaceous glands should be controlled with seaweed.
Seaweed bath:
Seaweed bath has certain
advantages, body relaxes and rids of itself of toxic matter and allows the
elements in seaweed to penetrate the skin. Certain oils can be combined with
seaweed to increases the properties of the bath. Seaweed baths were a common
feature of seaside resorts offering seaweed baths in seawater using steamed serrated
wrack - Fucus serratus - freshly collected
from the shore nearby. Seaweed and seaweed extracts are good for the skin is
beyond dispute according to cosmeticians and beauticians. Again, one can only
assume that alginates, carrageenans and agars, found
in large quantities in many seaweeds, have a beneficial effect in combination
with warm seawater; however, it is probable that there are other constituents
of seaweeds that have restorative powers.
CONCLUSION:
Seaweed
as either food or in supplement form or ingredient form may provide useful
additional therapy for treating many infections and some cancers. The
seaweed contains some important contents like proteins, lipids, minerals,
polysaccharides, enzymes and vitamins so it can be use for ingredients in beauty treatments and
also as neutraceuticals. The present limited use needs to be
diversified into other contemporary areas of application. Other benefits
include mild antihypertensive- and cholesterol-reducing effects. These seaweed
also provide valuable mineral supplementation. The seaweeds are one of the
important marine living resources could be termed as the futuristically
promising plants. Being a plant of unique structure and biochemical
composition, seaweed could be exploited for its multi-functional properties in
the form of dietary, medicinal and cosmetics applications.
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Received on 09.05.2013
Modified on 05.06.2012
Accepted on 12.06.2013
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Research Journal of
Pharmacognosy and Phytochemistry. 5(4): July- August 2013, 208-212