Author(s): A. V. Deokar, P. V. Bhosle

Email(s): pallavi.1230@gmail.com , arundhati.deokar@gmail.com

DOI: 10.52711/0975-4385.2021.00018   

Address: A. V. Deokar*, P. V. Bhosle
Shreeyash Institute of Pharmacetical Education and Research, Aurangabad, Maharashtra, India.
*Corresponding Author

Published In:   Volume - 13,      Issue - 3,     Year - 2021


ABSTRACT:
There are several medicinal plants having various medicinal properties is being widely used in Ayurveda which contain phytoconstituents. These phytoconstituents are beneficial to manage allied symptoms in psychosis andto treat abnormal condition of the mindthereby promoting mental well being. Argyreia nervosa (L.f) the ancient traditional medicinal plant belonging to the convolvulaceae family having prominent, psychedelic and neuro-pharmacological actions on our body. Argyreia nervosa seeds contain hallucinogens including ergot alkaloids such as ergine and Argoclavine and a naturally occurring lysergic acid amide. The current study describes pharmacognostic and phytochemical screening on Seeds of Argyreia nervosa. Argoclavine was extracted from the seeds and then characterised by different spectroscopic techniques like UV, IR, LC-MS. The results of the present study will create a way for the invention of novel herbal medicines for several ailments by using Argyreia nervosa seeds.


Cite this article:
A. V. Deokar, P. V. Bhosle. Phytochemical and Spectral analysis of Argoclavine; A potent Psychoactive substance present in the seeds of Argyreia nervosa plant. Research Journal of Pharmacognosy and Phytochemistry. 2021; 13(3):109-4. doi: 10.52711/0975-4385.2021.00018

Cite(Electronic):
A. V. Deokar, P. V. Bhosle. Phytochemical and Spectral analysis of Argoclavine; A potent Psychoactive substance present in the seeds of Argyreia nervosa plant. Research Journal of Pharmacognosy and Phytochemistry. 2021; 13(3):109-4. doi: 10.52711/0975-4385.2021.00018   Available on: http://rjpponline.org/AbstractView.aspx?PID=2021-13-3-1


REFERENCES:
1.    Joseph A, et al. Medicinal uses and biological activities of Argyreia speciosa Sweet (Hawaiian Baby Woodrose). Indian Journal of Natural Products and Resources Vol. 2(3): 286-291
2.    Juszczak GR, et al. Recreational use of D-lysergamide from the seeds of Argyreia nervosa, Ipomoea tricolor, Ipomoea violacea, and Ipomoea purpurea in Poland. J Psychoactive Drugs. 2013 Jan-Mar; 45(1): 79-93. doi: 10.1080/02791072.2013.763570. PMID: 23662334.
3.    Joseph A, et al. Medicinal uses and biological activities of Argyreia speciosa Sweet (Hawaiian Baby Woodrose). Indian Journal of Natural Products and Resources Vol. 2(3): 286-291
4.    Markert A, et al. Biosynthesis and accumulation of ergoline alkaloids in a mutualistic association between Ipomoea asarifolia (Convolvulaceae) and a clavicipitalean fungus. Plant Physiol. 2008 May;147(1):296-305. doi: 10.1104/pp.108.116699. Epub 2008 Mar 14. PMID: 18344419; PMCID: PMC2330284.
5.    Steiner U, et al. Ergoline alkaloids in convolvulaceous host plants originate from epibiotic clavicipitaceous fungi of the genus Periglandula. Fungal Ecology, doi:10.1016/j. funeco.2011.04.004
6.    Ahimsa-Müller MA, et al. Clavicipitaceous fungi associated with ergoline alkaloid-containing convolvulaceae. J Natural Prod. 2007;70(12): 1955–60
7.    Nair GG, et al. (1987) Ergolines in the seeds of some Indian Convolvulaceae.Indian J Pharm Sci; 49: 100-2.
8.    Yadav C*, et al. (2017) A review on Argyreia speciosa (l.f.) sweet. (vrdhhadaru): plant of Indian medical lexicons. International Journal of Ayurveda and Pharma Research; 5(4): 66-72
9.    Paulke A, et al. (2013) Argyreia nervosa (Burm. f.): Receptor profiling of Lysergic acid amide and other potential psychedelic LSD-like compounds by computational and binding assay approaches. Journal of Ethnopharmacology, 9; 148(2): 492-7
10.    Dr. Lohar D; (2008) Protocol for Testing Ayurvedic, Siddha and Unani Medicines; Government of India Department of AYUSH, Ministry of Health and Family Welfare, Pharmacopoeial Laboratory for Indian Medicines Ghaziabad; Research Gate 69-72.
11.    Thilagavathi.T et al. (2015) Preliminary phytochemical screening of different solvent mediated medicinal plant extracts evaluated, Int. Res. J. Pharm., 6 (4)
12.    Paulke A, et al. (2015) Studies on the alkaloid composition of the Hawaiian Baby Woodrose Argyreia nervosa, a common legal high. Forensic Sci Internat; 249: 281–93.
13.    Ara H, Jew‐Ming Chao, (1973) Ergoline alkaloidal constituents of hawaiian baby wood rose, Argyreia nervosa (Burm. f.) bojer, Journal of Pharmaceutical Science, doi.org/10.1002/ jps.2600620409.
14.    Paulke A et al. (2014) Identification of legal highs-ergot alkaloid patterns in two Argyreia nervosa products. Forensic Science International; 242: 62-71
15.    Ara H, Jew‐Ming Chao, (1973) Ergoline alkaloidal constituents of hawaiian baby wood rose, Argyreia nervosa (Burm. f.) bojer, Journal of Pharmaceutical Science, doi.org/10.1002/jps.2600
16.    Thilagavathi.T et al. (2015) Preliminary phytochemical screening of different solvent mediated medicinal plant extracts evaluated, Int. Res. J. Pharm., 6(4): 246-248
17.    Deokar A, Bhosle P. (2021) Formulation and Evaluation of Biogenic Silver Nanoparticles from Argoclavine and Flavonoids Obtained from of the Plant Parts of Argyreia nervosa. Inventi Rapid: NDDS, (2): 1-9
18.    Chao JM et al. The isolation and identification of the ergoline alkaloids from Ipomoea muelleri. Planta Med. 1974 Feb;25(1):6-16. doi: 10.1055/s-0028-1097906. PMID: 4818014.
19.    Chao JM et al. Isolation and identification of ergoline alkaloids from seeds of Stictocardia campanulata (L.) Merrill. Planta Med. 1979 Mar; 35(3): 247-52. doi: 10.1055/s-0028-1097212. PMID: 432303.
20.    Miller MD, Isolation and identification of lysergic acid amide and isolysergic acid amide as the principal ergoline alkaloids in Argyreia nervosa, J Assoc Offic Anal Chem, 1970, 53, 123-127
21.    Bryła M et al. (2015) Application of liquid chromatography/ion trap mass spectrometry technique to determine ergot alkaloids in grain products. Food Technol Biotechnol; 53(1): 18–28.
22.    Julia N et al. (2016) Identification and determination of ergot alkaloids in Morning Glory cultivars, Anal bioanal chemistry, 408(12): 3093-102

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