K.V.V.S. Krishna, P. Ajay Kumar, P. Akhila, N. Samhitha, P.N.S.G. Suryaveni, P. Harika Kumari, P. Sandeep Kumar.
K.V.V.S. Krishna*, P. Ajay Kumar, P. Akhila, N. Samhitha, P.N.S.G. Suryaveni, P. Harika Kumari, P. Sandeep Kumar.
Department of Pharmacognosy, Aditya College of Pharmacy, Surampalem, East Godavari District, Andhra Pradesh, India - 533 437.
Volume - 11,
Issue - 2,
Year - 2019
Panchachurnam is one of the classical Ayurvedic preparations traditionally used as laxative; it is prepared by mixing equal proportions of powdered Cassia angustifolia Vahl. leaf, Terminalia chebula Retz. fruit, Zingiber officinale Rosc. rhizome, Foeniculum vulgare Mill. fruit and Saindhava lavana. Even though this drug has been used based on traditional knowledge, no scientific work has been done to evaluate its laxative activity. Therefore, the aqueous extract of Panchachurnam was analyzed for its laxative activity using Wistar rats and it has shown significant action at all the tested doses when compared to standard and control, while highest activity exhibited by the higher concentration (400mg/ml) which assures the ethno-medicinal claim. The present study suggested that, Panchachurnam has great potential as a laxative and can be used as an alternative medicine in the treatment of constipation.
Cite this article:
K.V.V.S. Krishna, P. Ajay Kumar, P. Akhila, N. Samhitha, P.N.S.G. Suryaveni, P. Harika Kumari, P. Sandeep Kumar. Evaluation of Laxative Activity of Panchachurnam: an Ayurvedic Polyherbomineral Formulation. Res. J. Pharmacognosy and Phytochem. 2019; 11(2):93-96. doi: 10.5958/0975-4385.2019.00017.7