Volume No. :   8

Issue No. :  3

Year :  2016

ISSN Print :  0975-2331

ISSN Online :  0975-4385


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Phytochemical and Toxicological Evaluation of Acorus calamus and Argyreia speciosa Leaves Extract



Address:   Patil P.J.1, Patil V.R.2
1Marathwada Mitra Mandal’s College of Pharmacy, Thergaon (Kalewadi), Pune-411 033, Maharashtra, India.
2Tapi Valley Education Society’s Hon. Loksevak Madhukarrao Chaudhari College of Pharmacy, Faizpur Dist: Jalgaon-425 503, Maharashtra, India.
*Corresponding Author
DOI No: 10.5958/0975-4385.2016.00022.4

ABSTRACT:
In present study Acorus calamus and Argyreia speciosa were collected, their authentications were performed. These two plants were extracted by three different solvents. Extracts of these plants were subjected to different phytochemical analysis. Acute toxicity studies of these plant extracts were performed to determine their safety. Phytochemical Investigation were carried out by performing various tests viz. test for detection of carbohydrate, alkaloid, proteins, volatile oils, flavonoids, saponins, phenols, resins, tannins, amino acid, steroids, triterpenoids, anthraquinones and coumarines. Acute oral toxicity was performed using OECD 420 guidelines. Groups of female rats are dosed in a stepwise procedure using the fixed doses of 5, 50, 300 and 2000 mg/kg. No toxic symptoms or mortality were observed in any animals, which lived up to 14 days after the administration of all extract of AC and AS upto the level of 2000 mg/kg body weight
KEYWORDS:
Acorus calamus, Argyreia speciosa, Phytochemical, Toxicological
Cite:
Patil P.J., Patil V.R. Phytochemical and Toxicological Evaluation of Acorus calamus and Argyreia speciosa Leaves Extract. Res. J. Pharmacognosy and Phytochem. 2016; 8(3): 121-124.
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