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Volume No. :   8

Issue No. :  3

Year :  2016

ISSN Print :  0975-2331

ISSN Online :  0975-4385


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Characterization of Annona muricata stem methanol extract by gas chromatography–mass spectrometry analysis



Address:   Okoro Ebere Kelechi, Amaku Friday James, Okoro Innocent Ajah
Department of Chemistry, Michael Okpara University of Agriculture, Umudike, Nigeria
*Corresponding Author
DOI No: 10.5958/0975-4385.2016.00028.5

ABSTRACT:
Annona muricata extract are extensively used as traditional remedy for a variety of illnesses like cancer, diabetes, hypertension and malaria. Methanol extract of Annona muricata (soursop) stem were analyzed using gas chromatography–mass spectrometry method. The result obtained from the GC-MS analysis of methanol extract of Annona muricata stem led to identification of ten (10) compounds in which 1-(4-hydroxy-6-methyl-2-pyrimidinyl)-2-aziridinone, hexadecanoic acid (palmitic acid) and 9-octadecanoic acid(oleic acid) are the major component reported with significant bioactive impact. The components were identified by comparing their retention indices and mass spectra fragmentation patterns with those stored in the National Institute of Standards and Technology (NIST) library.
KEYWORDS:
Chromatogram, Annona muricata, retention indices, mass spectra
Cite:
Okoro Ebere Kelechi, Amaku Friday James, Okoro Innocent Ajah. Characterization of Annona muricata stem methanol extract by gas chromatography–mass spectrometry analysis. Res. J. Pharmacognosy and Phytochem. 2016; 8(3): 165-171.
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