Volume No. :   6

Issue No. :  1

Year :  2014

ISSN Print :  0975-2331

ISSN Online :  0975-4385


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Anti-Inflammatory Activity of Some Indigenous Sudanese Plants

Address:   Sara M.O. Ismaiel1, Elhadi N. Mahmoud2*, Abdelkhalig M. Mahmoud1
1College of Pharmacy, University of Khartoum, Sudan
2College of Pharmacy and Health Sciences, Ajman University of Science and Technology Network (UAE)
*Corresponding Author

Three medicinal plant extracts from Sudan, used in traditional medicine, were investigated for their anti-inflammatory activity against carrageenan-induced inflammation. The present study is an endeavor to evaluate the anti-inflammatory activity of methanolic extract of Solenostemma argel leaves, Hordeum vulgare grains and Ziziphus spina-christi fruits. The anti-inflammatory activity of the extracts was evaluated using the carrageenan-induced Wister rats edema model. Among the extracts, the S. argel extract at a dose of 100 mg/kg body weight exhibited an inhibition of inflammation after 3hr (22%) of carrageenan administration. The most significant inhibition was revealed by the Z. spina-christi after 1 hr. (55%), at a dose of 100 mg/kg body weight, whilst the extract of H. vulgare grains had no effect on the edema at the same concentration.
plant extracts activity; Sudanese medicinal plants; anti-inflammatory activity.
Sara M O Ismaiel, Elhadi N. Mahmoud, Abdelkhalig M. Mahmoud. Anti-Inflammatory Activity of Some Indigenous Sudanese Plants. Res. J. Pharmacognosy & Phytochem. 2014; 6(1): 30-32.
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