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Research Journal of Pharmacognosy and Phytochemistry
ISSN: 0975-4385(Online), 0975-2331(Print)
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Anti-Inflammatory Activity of Some Indigenous Sudanese Plants
Sara M O Ismaiel
Elhadi N. Mahmoud
Abdelkhalig M. Mahmoud
Sara M.O. Ismaiel1, Elhadi N. Mahmoud2*, Abdelkhalig M. Mahmoud1
1College of Pharmacy, University of Khartoum, Sudan
2College of Pharmacy and Health Sciences, Ajman University of Science and Technology Network (UAE)
Three medicinal plant extracts from Sudan, used in traditional medicine, were investigated for their anti-inflammatory activity against carrageenan-induced inflammation. The present study is an endeavor to evaluate the anti-inflammatory activity of methanolic extract of Solenostemma argel leaves, Hordeum vulgare grains and Ziziphus spina-christi fruits. The anti-inflammatory activity of the extracts was evaluated using the carrageenan-induced Wister rats edema model. Among the extracts, the S. argel extract at a dose of 100 mg/kg body weight exhibited an inhibition of inflammation after 3hr (22%) of carrageenan administration. The most significant inhibition was revealed by the Z. spina-christi after 1 hr. (55%), at a dose of 100 mg/kg body weight, whilst the extract of H. vulgare grains had no effect on the edema at the same concentration.
plant extracts activity; Sudanese medicinal plants; anti-inflammatory activity.
Sara M O Ismaiel, Elhadi N. Mahmoud, Abdelkhalig M. Mahmoud. Anti-Inflammatory Activity of Some Indigenous Sudanese Plants. Res. J. Pharmacognosy & Phytochem. 2014; 6(1): 30-32.
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