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Research Journal of Pharmacognosy and Phytochemistry
ISSN: 0975-4385(Online), 0975-2331(Print)
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Phytochemical studies and in vitro Anti-inflammatory activity of Melia azedarach (L) flower
M. Sinthanai Selvi
S. Sumathi1*, M. Sinthanai Selvi2
1Guest Lecturer, Department of Biochemistry, Dharamapuram Gnanambigai Govt. Arts College, Mayiladuthurai India-609001
2Department of Biochemistry, Dharamapuram Gnanambigai Govt. Arts College, Mayiladuthurai India-609001
Physiochemical parameters such as colour, taste, odour, ash values, moisture content were determined. Carbohydrate and protein content were also determined. Various colour change were observed when treated with different chemical reagents and Preliminary phytochemical screening showed the presence of alkaloids, flavonoids, terpenoids, anthraquinonens, tannins, saponins and cardic glycosides. The aqueous extracts of the flower of Melia azedarach (L) were studied for in vitro anti-inflammatory activity by HRBC membrane stabilization method. The flower extract exhibited membrane stabilization effect by inhibiting hypotonicity induced lysis of erythrocyte membrane. The aqueous extract shows significant anti inflammatory activity at the concentration of 800 µg /ml which is comparable to the standard drug (Diclofenac sodium 200µg/ml)The anti inflammatory activity of the extracts were concentration dependent, with the increasing concentration the activity is also increased.
Phytochemicals, Melia azedarach, anti inflammatory.
S. Sumathi, M. Sinthanai Selvi. Phytochemical studies and in vitro Anti-inflammatory activity of Melia azedarach (L) flower. Res. J. Pharmacognosy & Phytochem. 2014; 6(1): 19-21.
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