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Volume No. :   5

Issue No. :  3

Year :  2013

ISSN Print :  0975-2331

ISSN Online :  0975-4385


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In-vitro screening of Ficus racemosa for Anticancer activity



Address:   Prakash S. Sukhramani 1*, G. Vidyasagar2, Piyush M. Patel3
1Ph.D. Research Scholar, JJT University, Vidyanagari, Jhunjhunu – Churu Road, Dist: Jhunjhunu, Rajasthan – 333001, India
2Veerayatan Institute of Pharmacy, Bhuj-Mandvi Road, Jakhania, Mandvi – 370460, Dist: Kutch, Gujarat, India
3Shree B.M Shah College of Pharmaceutical Education and Research, Modasa - 383315, Dist: Sabarkantha, Gujarat, India
DOI No:

ABSTRACT:
Ficus racemosa is a moderate sized avenue tree found throughout India. It is popular in indigenous system of medicine like Ayurveda, Siddha, Unani and Homoeopathy. Aim of the present study was undertaken with an objective to find out the anticancer activity of Ficus racemosa plant extracts using standard in-vitro MTT bioassay against various cancer cell lines (HL-60, HepG2, NCI-H23 and HEK-293T). With use of MTT dye, % cell viability and % inhibition of the hit compounds was evaluated within respective wavelengths prior with standard compounds. Data obtained from MTT bioassay screening revealed that methanolic extract of Ficus racemosa shown cytotoxic activity against HL-60 and HepG2 cell line with profound IC50 values and shown negligible toxicity against normal cell line (HEK-293T).
KEYWORDS:
Ficus racemosa Linn., MTT bioassay, anticancer activity
Cite:
Prakash S. Sukhramani , G. Vidyasagar, Piyush M. Patel. In-vitro screening of Ficus racemosa for Anticancer activity. Research J. Pharmacognosy and Phytochemistry 2013; 5(3): 119-122.
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