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Volume No. :   4

Issue No. :  2

Year :  2012

ISSN Print :  0975-2331

ISSN Online :  0975-4385


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The Wound healing, anti inflammatory and haemostatic effect of Eupatorium odoratum



Address:   R. Suresh*, D. Benito Johnson, Appalaraju Gorle, Ashok Kumar Javvadi, Tamil Selvan A.
Department of Pharmacology, R.V.S. College Pharmaceutical Science, Sulur, Coimbatore-640 402
*Corresponding Author:
DOI No:

ABSTRACT:
Wound is perhaps an inescapable event in the life of an organism. Healing process begins during the early phase of inflammation, but reaches completion usually after the injurious influence has been neutralized. It should be emphasized that without inflammation wounds would never heal. Eupatorium odoratum Linn. (Family: Compositae) is a perennial herb growing widely in the south of the country. The wound healing effect of ethanol extract of E. odoratum was studied using, re sutured incision wound, excision wound model, dead space wound model and the results obtained by the three models were compared and found that excision wound model is statistically significant (p<0.01). The anti inflammatory activity of ethanol- leaf extract of E. odoratum was evaluated using carregeenan induced paw edema in rats, there was no statistically significant change in the drug treated compared to the control and the haemostatic activity assessed by capillary tube method, there was a statically significant reduction in the blood coagulation time.
KEYWORDS:
wound healing, anti inflammatory, haemostatic, Eupatorium odoratum.
Cite:
R. Suresh, D. Benito Johnson, Appalaraju Gorle, Ashok Kumar Javvadi, Tamil Selvan A. The Wound healing, anti inflammatory and haemostatic effect of Eupatorium odoratum. Research J. Pharmacognosy and Phytochemistry 2012; 4(2): 75-79.
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