Volume No. : 3
Issue No. : 6
Year : 2011
ISSN Print : 0975-2331
ISSN Online : 0975-4385
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Evaluation of Wound Healing Activity of Isolated Compound Quercetin and Alcoholic Extract of Leaves of Mussaenda frondosa Linn.
Patil Suhas A.1*, Joshi V.G.2 and Sambrekar S.N.3
1Dept. of Pharmacognosy, Maratha Mandal’s College of Pharmacy, Belgaum, India.
2Dept. of Pharmaceutics. Government College of Pharmacy, Bengaluru, India
3Dept. of Pharmacology, Maratha Mandal’s College of Pharmacy, Belgaum, India.
*Corresponding Author
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DOI No:
ABSTRACT:
Since the time immemorial, our traditional system of medicine and folklore claiming that medicinal plants as a whole or their parts are being used in all types of diseases. Natural remedies from medicinal plants are considered to be effective and safe alternative treatment for wounds. Alcoholic extract of leaves of Mussaenda frondosa Linn. (Rubiaceae) and its isolated compound quercetin were evaluated for wound healing activity by using different types of wound healing models such as excision wound, incision wound and dead space wound. The results were obtained in terms of wound contraction, epithelialization time and tensile strength. All results were significant for different parameters in wound healing activity in quercetin and alcoholic extract treated animals compared with control groups. The isolated compound quercetin was confirmed by preliminary phytochemical investigation, IR, NMR and Mass spectroscopic methods.
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KEYWORDS:
Mussaenda frondosa Linn, wound healing activity, alcoholic extract, quercetin.
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Cite:
Patil Suhas A., Joshi V.G., Sambrekar S.N. Evaluation of Wound Healing Activity of Isolated Compound Quercetin and Alcoholic Extract of Leaves of Mussaenda frondosa Linn. Research J. Pharmacognosy and Phytochemistry 2011; 3(6): 266-271.
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