Author(s): Harsha Leena K., Kambhoja S., Vishesh Upadhyay.

Email(s): harshaleena.14@gmail.com ,

DOI: Not Available

Address: Harsha Leena K.*, Kambhoja S. and Vishesh Upadhyay.
Department of Pharmacognosy, The Oxford College of Pharmacy, Hongasandra, Bangalore- 560068, Karnataka.
*Corresponding Author

Published In:   Volume - 3,      Issue - 4,     Year - 2011


ABSTRACT:
Alstonia scholaris Linn. R. Br. also called as Devil’s tree and Dita bark belongs to the family Apocyanaceae. It is a large, ever green tree, found almost throughout India up to an altitude, 600m. The bark was collected and authenticated by Dr. Madhava Chetty, Sri Venkateshwara University, Tirupathi. The antibacterial activity of the stem bark of Alstonia scholaris Linn. R. Br. was investigated as there is a necessity for the search of new antibiotics as the infectious diseases continue to be the major concern for health institutions, pharmaceutical companies and Governments all over the world, especially with the current increasing trends of multidrug resistance among emerging – reemerging bacterial pathogens to the available modern drug or antibiotics. The plants are the cheapest and safe alternative source of antimicrobials. The powder of the dried stem bark was extracted with different solvents in increasing order of the polarity by soxhelation. Antibacterial activity was tested against both Gram positive (Staphylococcus aureus, Bacillus subtilis) and Gram negative (Pseudomonas aeruginosa, Escherichia coli) organisms using agar disc diffusion method. The methanol and benzene extracts exhibited significant antibacterial activity against Gram negative bacteria and ethanol extract against Gram positive bacteria. Chloroform and acetone extracts exhibited less activity, while petroleum ether and aqueous extracts showed no zone of inhibition. The results were compared with the standard drug, Ampicillin.


Cite this article:
Harsha Leena K., Kambhoja S. , Vishesh Upadhyay. Evaluation of Antibacterial Activity of the Stem Bark of Alstonia scholaris Linn. R.Br. Research J. Pharmacognosy and Phytochemistry 2011; 3(4): 180-183.


Recomonded Articles:

Author(s): Ravindra Singh, Aakanksha Tiwari

DOI: 10.5958/0975-4385.2016.00036.4         Access: Open Access Read More

Author(s): Dev Raj Sharma, Amit Sharma, Ankaj Kaundal, Puneet Kumar Rai

DOI:         Access: Open Access Read More

Author(s): Bhavna Patel, Gopi Patel, Samir Shah, Shraddha Parmar

DOI: 10.5958/0975-4385.2017.00046.2         Access: Open Access Read More

Author(s): Shikha Srivastava, Nidhi Mishra

DOI:         Access: Open Access Read More

Author(s): Umesh Annappan, Vijaya Bharathi Rajkishore, Radha Ramalingam

DOI: 10.5958/0975-4385.2015.00034.5         Access: Open Access Read More

Author(s): D. Esther Lydia, Sheila John, Swetha V K, Thiyagarajan Sivapriya

DOI: 10.5958/0975-4385.2017.00045.0         Access: Open Access Read More

Author(s): Kalpana Patil, Swati Dhande, Vilasrao Kadam

DOI:         Access: Open Access Read More

Author(s): Gharge Varsha G., Shelar Pournima A., Ghadge Dhairysheel M., Patil Anup A., Bhandwalkar Omkar S., Yadav Adhikrao V.

DOI: 10.5958/0975-4385.2017.00016.4         Access: Open Access Read More

Author(s): K Mekala, R Radha

DOI: 10.5958/0975-4385.2015.00035.7         Access: Open Access Read More

Author(s): Anil Kumar Aher, Subodh Pal, Sadahev Yadav, Umesh Patil, Snehendu Bhattacharya

DOI:         Access: Open Access Read More

Author(s): Shubhashree M N, Venkateshwarlu G, Doddamani S H

DOI:         Access: Open Access Read More

Author(s): Sanjoy Das1, Tejendra Bhakta

DOI: 10.5958/0975-4385.2018.00038.9         Access: Open Access Read More

Author(s): V. Alamelu , T. Ananthi

DOI:         Access: Open Access Read More

Author(s): Sul S. R, Shaikh K. B, Pandhare Y. L, Kale V. M., Nagansurkar S.

DOI: 10.5958/0975-4385.2018.00025.0         Access: Open Access Read More

Author(s): Stellaa Robertson,Narayanan N

DOI:         Access: Open Access Read More

Author(s): Mohini Upadhye, Parikshit Gandhi, Mohini Phanse

DOI:         Access: Open Access Read More

Author(s): Varun Chaddha, Avinash Singh Kushwah, Vaibhav Srivastava

DOI:         Access: Open Access Read More

Author(s): Pinkie Cherian, D. Sheela

DOI: 10.5958/0975-4385.2017.00040.1         Access: Open Access Read More

Author(s): Akshada A Koparde, C S Magdum

DOI:         Access: Open Access Read More

Research Journal of Pharmacognosy and Phytochemistry (RJPP) is an international, peer-reviewed journal, devoted to pharmacognosy...... Read more >>>

RNI: Not Available                     
DOI: 10.5958/0975-4385 


Recent Articles




Tags