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Research Journal of Pharmacognosy and Phytochemistry
ISSN: 0975-4385(Online), 0975-2331(Print)
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Analgesic Activity of the Isolated Constituent Syzygium cuminii (L) skeel
Nikhat F.*, Satyanarayana D., Suresh D.K., Purohit M.G., Raza H. and Hamza S.M.
Department of Pharmaceutical Chemistry, Luqman College of Pharmacy Gulbarga-585201
The present study was carried out to investigate the analgesic activity of the prepared formulation 50mg/kg and 200mg/kg body weight in the form of gel on albino rats by Tail immersion method. The different dose level of prepared gel was applied to the rat according to the body weight to the tail which is marked at 5cm and was subjected to analgesic activity. The significance analgesic activity is observed after ½ hr of the application which was compared with standard dichlofenac gel, the activity decreased after 2 hr of the application. The gel was prepared from the isolated constituents of syzygium cuminii (L) skeel root extract. The aim of the work is to prepare such a formulation which is having natural analgesic activity. The expected result from the formulation was obtained for first time. The further work is going on in our laboratory.
Analgesic, dichlofenac gel, formulation, constituents.
Nikhat F., Satyanarayana D., Suresh D.K., Purohit M.G., Raza H. , Hamza S.M. Analgesic Activity of the Isolated Constituent Syzygium cuminii (L) skeel. Research J. Pharmacognosy and Phytochemistry 2011; 3(4): 178-179.
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