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Research Journal of Pharmacognosy and Phytochemistry
ISSN: 0975-4385(Online), 0975-2331(Print)
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Hepatoprotective Activity of Prunus persica Peaches against Paracetamol Induced Hepatotoxicity.
S. Manokaran*, V.S. Saravanan and Y. Bhargavi.
The Erode College of Pharmacy, Tamilnadu
Hepato- toxicity is a common toxicity happening during the treatment of chronic disease like tuberculosis, diabetics. Prunus persica belongs to Rosaceae is a plant growing in temperate region has laxative , sedative, anti-cancer property and also consist of glycosides, flavonoids, anthocyanins, vitamins. It also posses hepato-protactent property. To prove the activity scientifically the ethanolic extract of Prunus persica was studied against paracetamol induced hepatotoxicity in albino rats. The extract when evaluated at dose of 100mg/ kg was found to significantly reduce the elevated levels of serum lysosomal enzyme Sgpt, Sgot, Alp and Bilirubin when compared with standard silymarin.
Prunus persica, paracetamol, albino rats, serum enzymes.
S. Manokaran, V.S. Saravanan , Y. Bhargavi. Hepatoprotective Activity of Prunus persica Peaches against Paracetamol Induced Hepatotoxicity. Research J. Pharmacognosy and Phytochemistry 2011; 3(2): 75-76 .
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