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Volume No. :   3

Issue No. :  2

Year :  2011

ISSN Print :  0975-2331

ISSN Online :  0975-4385


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Hepatoprotective Activity of Prunus persica Peaches against Paracetamol Induced Hepatotoxicity.



Address:   S. Manokaran*, V.S. Saravanan and Y. Bhargavi.
The Erode College of Pharmacy, Tamilnadu
*Corresponding Author
DOI No:

ABSTRACT:
Hepato- toxicity is a common toxicity happening during the treatment of chronic disease like tuberculosis, diabetics. Prunus persica belongs to Rosaceae is a plant growing in temperate region has laxative , sedative, anti-cancer property and also consist of glycosides, flavonoids, anthocyanins, vitamins. It also posses hepato-protactent property. To prove the activity scientifically the ethanolic extract of Prunus persica was studied against paracetamol induced hepatotoxicity in albino rats. The extract when evaluated at dose of 100mg/ kg was found to significantly reduce the elevated levels of serum lysosomal enzyme Sgpt, Sgot, Alp and Bilirubin when compared with standard silymarin.
KEYWORDS:
Prunus persica, paracetamol, albino rats, serum enzymes.
Cite:
S. Manokaran, V.S. Saravanan , Y. Bhargavi. Hepatoprotective Activity of Prunus persica Peaches against Paracetamol Induced Hepatotoxicity. Research J. Pharmacognosy and Phytochemistry 2011; 3(2): 75-76 .
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