Volume No. :   3

Issue No. :  1

Year :  2011

ISSN Print :  0975-2331

ISSN Online :  0975-4385


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Effect of leave Extract of Prunus persica Linn on Acute Inflammation in Rats

Address:   Chiranjib Bhattacharjee1*, Durgesh Gupta2, Lokesh Deb3, Santhosh Kumar C1, Subal Debnath1 and A.S.Dutta4.
1Sri Krupa Institute of Pharmaceutical Sciences, Vil. Velkatta, Kondapak (Mdl), Dist. Medak, Siddipet. Andhra Pradesh – 502277, India.
2Rajiv Gandhi College of Pharmacy, Nautanwa, Maharajganj, UP– 273164, India.
3I.B.S.D. Takyelpat ,Imphal, Manipur, India
4R. K. Pharmacy College, Kasipur, Suri – Santhiaon, Azamgarh, UP–276001, India.
*Corresponding Author:

Prunus persica Linn (L) widely distributed in Manipur, India. The leaves were used in folklore/traditional medicine to treat several inflammatory pathologies such as greenish swelling (gland), oedema etc. Reactive oxygen species as well as reactive free radicals such as hydroxyl (OH), nitric oxide (NO) etc. contribute significantly to these pathologies. In this study, anti-inflammatory activity of the aqueous extracts (AEPp) of Prunus persica L leaves was evaluated on carrageenin induced oedema. The test sample at the dose of 200 mg/kg/p.o. were found to cause significant (***P<0.001) inhibition of carrageenin induced oedema. The test samples AEPp show the protection against inflammation less than standard diclofenac sodium 8mg/kg b.w. These observations established the anti-inflammatory effect of Prunus persica L leaves aqueous extract in acute inflammation.
Prunus persica, inflammation.
Chiranjib Bhattacharjee, Durgesh Gupta, Lokesh Deb, Santhosh Kumar C, Subal Debnath, A.S.Dutta. Effect of leave Extract of Prunus persica Linn on Acute Inflammation in Rats. Research J. Pharmacognosy and Phytochemistry 2011; 3(1): 38-40.
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