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Research Journal of Pharmacognosy and Phytochemistry
ISSN: 0975-4385(Online), 0975-2331(Print)
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List of Refereed Journals published by UGC, New Delhi on 11-01-2017-- Research Journal of Pharmacy and Technology (Sr. No.-275); Asian Journal of Management (Sr. No.-3986); Asian Journal of Research in Chemistry (Sr. No.-4008); Research Journal of Engineering and Technology (Sr. No.-31787); Researc
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Studies on Anti-Inflammatory and Analgesic Properties of Methanol Extract of Aerial Part of Clerodendrum inerme in Experimental Animal Models
R. Vijay Amirtharaj
R. Senthil Kumar
R. Vijay Amirtharaj*, V. Suresh and R. Senthil Kumar
Department of Pharmaceutical chemistry, JKKMMRF College of Pharmacy, Ethirmedu, Komarapalayam 638183, Namakkal Dt, Tamilnadu, India.
The methanol extract of aerial part of Clerodendrum inerme were investigated for anti-inflammatory and analgesic at the dose 200 mg/kg, body weight. The experimental paradigms used were carrageenan, induced pedal edema for anti-inflammatory activity, acetic acid induced writhing methods were used to assess analgesic activity. In acute phase inflammation, a maximum inhibition 60.17% (P < 0.01) was noted at the dose of 200 mg/kg after 3 h of treatment with methanol extract of Clerodendrum inerme (MECI) in carrageenan, induced pedal edema respectively. The extract also produced significant (P < 0.01) analgesic activity in both paradigms. This study exhibits that the methanol extracts of aerial part of Clerodendrum inerme possess anti-inflammatory and analgesic activities.
Clerodendrum inerme, Anti-inflammatory, Analgesic
R. Vijay Amirtharaj, V. Suresh , R. Senthil Kumar. Studies on Anti-Inflammatory and Analgesic Properties of Methanol Extract of Aerial Part of Clerodendrum inerme in Experimental Animal Models. Research J. Pharmacognosy and Phytochemistry 2010; 2(5): 421-424.
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