Soosamma John, Madhavi T., Bincy Raj, Jincy Shaji, Vinutha
Soosamma John1*, Madhavi T.1, Bincy Raj2, Jincy Shaji1 and Vinutha3
1East Point college of Pharmacy, Bidarahalli, Bangalore-560049.
2Dayananda Sagar College of Pharmacy, Bangalore-560078,
3PES College of Pharmacy, Bangalore- 560059.
Volume - 2,
Issue - 4,
Year - 2010
Crataeva nurvala Buch. Ham. (Capparidaceae) is a high-value medicinal tree that grows almost all over India, especially in the semiarid regions. Medicinal usage has been reported in traditional systems of medicine, such as Ayurveda and Unani. This drug is used in traditional system of medicine against a wide variety of urinary disorders. Crataeva nurvala is commonly known as Varuna. Many phytoconstituents have been isolated from the fruits, root bark and stem bark of Varuna. Lupeol is the major chemical constituent isolated from Varuna. The minor chemical constituents are cadabicine, cadabicinediacetate, catechin, (-)epicatechin-5-glucoside, (-)epiafzelechin, glucocapparin, lupeol acetate, spinasterol acetate and taraxasterol. Lupeol, a pentacyclic triterpene isolated from the root bark, has been shown to significantly minimize the deposition of stone-forming constituents in kidneys. Investigations have also indicated the plant has anti-arthritic, hepatoprotective, and cardio-protective actions. This review briefly examines the Phytochemistry, biological activities, pharmacological actions, clinical studies, and medicinal applications of Crataeva nurvala to provide direction for further research.
Cite this article:
Soosamma John, Madhavi T., Bincy Raj, Jincy Shaji, Vinutha. Phytochemistry and Pharmacology of an Important Indian Medicinal Plant Crataeva nurvala Buch Ham. Research J. Pharmacognosy and Phytochemistry 2010; 2(4): 275-279.