Volume No. :   2

Issue No. :  3

Year :  2010

ISSN Print :  0975-2331

ISSN Online :  0975-4385


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Cucurbitacin Glycosides from the fruits of Citrullus colocynthis (L).

Address:   N. Sampath Kumar1* and G. Madhurambal2
1Department of Chemistry, Chettinad College of Engineering and Technology, Karur, 639114.
2ADM College for Women, Nagappattinam, 611 001
*Corresponding Author

Citrullus colocynthis (L.) Schrad. (Cucurbitaceae) is an Iranian medicinal plant that has traditionally been used as an abortifacient and to treat constipation, oedema, bacterial infections, cancer and diabetes. As part of our on-going studies on Iranian medicinal plants, thorough phytochemical investigation was carried out on this plant. Solvent extraction method was employed to isolate compounds from the ethyl acetate and ethyl methyl ketone fractions of the hydro-ethanolic (90%) extract of the fruits of the locally grown C. colocynthis. Structures of the isolated compounds were elucidated by spectroscopic means. Two cucurbitacin glucosides, 2-O-ß-D-glucopyranosylcucurbitacin I and 2-O-ß-D-glucopyranosylcucurbitacin L were isolated and identified.
Citrullus colocynthis, Cucurbitaceae, Cucurbitacin I, Cucurbitacin L
N. Sampath Kumar, G. Madhurambal. Cucurbitacin Glycosides from the fruits of Citrullus colocynthis (L). Research J. Pharmacognosy and Phytochemistry 2010; 2(3): 200-202.
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