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Research Journal of Pharmacognosy and Phytochemistry
ISSN: 0975-4385(Online), 0975-2331(Print)
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Evaluation of Antimicrobial activity of Tephrosia procumbens Buch –Ham
Faheem I. Patwekar
Mohsina F. Patwekar
Faheem I. Patwekar1*, Sanjeev Heroor2, Mohsina F. Patwekar1 and Muhammad Asif3
1Luqman College of Pharmacy, Gulbarga.
2HKES’s Society’s College of Pharmacy, Gulbarga.
3Allana College of Pharmacy, Pune.
In the present study, the entire plant of Tephrosia procumbens Buch-Ham commonly known as Vempalli, Indigo sauvage (Fam-Fabaceae/ Leguminosae) was investigated for the phytochemical screening and antimicrobial property against certain microorganisms using disc diffusion method. The entire plant of Tephrosia procumbens were collected, shade dried at room temperature, pulverized and extracted with 95% ethanol in soxhlet extractor to get total ethanolic extract which is further fractionated with the solvents of different polarities. Total aqueous extract was also obtained by macerating the shade dried material with 3% of chloroform water I.P. All the extracts and fractions were subjected for Preliminary Phytochemical screening, which has shown the presence of Carbohydrates, Steroids and Flavonoids and evaluation of antimicrobial property by using disc diffusion method on various pathogenic forms of microorganisms including gram positive, gram negative and fungi. It was found that total ethanolic and total aqueous extract of entire plant of Tephrosia procumbens significantly inhibit the growth of microorganisms as compared to standard drugs Gentamycin and streptomycin (Hi-Media Lab. Mumbai).
Tephrosia procumbens, Antimicrobial activity, .
Faheem I. Patwekar, Sanjeev Heroor, Mohsina F. Patwekar, Muhammad Asif. Evaluation of Antimicrobial activity of Tephrosia procumbens Buch –Ham. Research J. Pharmacognosy and Phytochemistry 2010; 2(3): 238-240.
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