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Research Journal of Pharmacognosy and Phytochemistry
ISSN: 0975-4385(Online), 0975-2331(Print)
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Antihyperglycemic Activity of Strychnos potatorum Seed and Leaf Methanolic Extracts in Alloxan- Induced Diabetic Rats
T Pandu Raju
C Srinivas Reddy
T Pandu Raju1*, KJR Shastri2 , C Srinivas Reddy1 and VM Reddy1
1Department of Pharmacognosy, Vaagdevi College of Pharmacy, Hanumakonda, Warangal, Andhra Pradesh, India.
2Department of Ayurvedic, Ananthalaxmi Ayurvedic Government Medical College, Warangal, Andhra Pradesh, India.
The pharmacognostic and phytochemical examinations of different solvents extracts of seeds and leaves of Strychnos potatorum were conducted and their antidiabetic activity was evaluated.The administration of methanolic extracts of seeds and leaves of Strychnos potatorum by oral route at doses; 200 and 400 mg/kg b.w. at every 3 hour interval reduced blood glucose levels by24.23%, 25.67%, 16.47% and 17.88%, respectively in alloxan-induced diabetic rats.
Strychnos potatorum; Alloxan; antihyperglycemic activity; Loganiaceae; MESP (methanolic extract of seed Powder); MELP (methanolic extract of leaf powder).
T Pandu Raju, KJR Shastri , C Srinivas Reddy, VM Reddy. Antihyperglycemic Activity of Strychnos potatorum Seed and Leaf Methanolic Extracts in Alloxan- Induced Diabetic Rats. Research J. Pharmacognosy and Phytochemistry 2010; 2(2): 152-154.
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