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Research Journal of Pharmacognosy and Phytochemistry
ISSN: 0975-4385(Online), 0975-2331(Print)
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Hypoglycemic Activity of Erythrina varigata in Alloxan Induced Diabetic Mice
Uma Maheswara Reddy C
Vedhapal Jeyamani S
Babu Ananth D
Murugan M1, Uma Maheswara Reddy C2, Vedhapal Jeyamani S1, Babu Ananth D1 and Umasankar K1
1Maharaji College of Pharmacy, Chennai-600 090, India.
2Sri Ramachandra College of Pharmacy, Chennai 600 116, India
Ethanolic leaf extract of Erythrina varigata was carried out using soxhlet apparatus. The extract was evaluated for preliminary phytochemical studies, acute toxicity studies and hypoglycemic activity. Acute toxicity study revealed that the ethanolic leaf extract even at high dose (2000mg/ kg) produced no death and found to be safe. The hypoglycemic activity was evaluated in normal and alloxan induced diabetic mice. The chloroform fraction of the leaf extract was found to possess significant hypoglycemic activity when compared to standard Glibenclamide.
Erythrina varigata, hypoglycemic activity, Diabetes mellitus.
Murugan M, Uma Maheswara Reddy C, Vedhapal Jeyamani S, Babu Ananth D, Umasankar K. Hypoglycemic Activity of Erythrina varigata in Alloxan Induced Diabetic Mice. Research J. Pharmacognosy and Phytochemistry 2010; 2(1): 89-90.
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