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Volume No. :   2

Issue No. :  1

Year :  2010

ISSN Print :  0975-2331

ISSN Online :  0975-4385


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Evaluation of Anti Bacterial and Anti Platelet Activity of Ethanolic Leaf Extract of Physalis angulata



Address:   Jafferi SAH1, *Sandhya S1, Vinod KR1, Narender Prasad D1 and Venkataramana K2
1Nalanda College of Pharmacy, Nalgonda, A.P
2ASN Pharmacy College, Tenali, A.P
*Corresponding Author
DOI No:

ABSTRACT:
There has always been a closed association between plants and human beings through ancient time and till date. Physalis angulata is an annual herb indigenous to many parts of the tropics, including the Amazon. It can be found on most continents in the tropics, including Africa, Asia, and the Americas. It grows up to 1 m high, bears small, cream-colored flowers, and produces small, light yellowish-orange, edible fruit sometimes referred to as Cutleaf Groundcherry. It is a popular medicine used due to its anti-inflammatory effects, anti tumor effects, immunomodulatory effects etc. The present study is to evaluate the anti bacterial and anti platelet activity of the ethanolic leaf extract of Physalis angulata. From the phytochemical screening it was found that the plant is mainly constituted with phenols, steroids and flavonoids .The anti bacterial activity was performed by well diffusion method on various concentrations of the extract. Gentamycin was used as the standard and ethanol as the control. In the antiplatelet activity study, the platelet was induced using adenosine di phosphate. Nephlometer was used to observe the aggregation. It was observed that the ethanolic leaf extract showed pronounced anti platelet activity. But the anti bacterial activity was found to be false positive.
KEYWORDS:
Physalis angulata, anti-platelet, anti bacterial, nephlometer
Cite:
Jafferi SAH, Sandhya S, Vinod KR, Narender Prasad D, Venkataramana K. Evaluation of Anti Bacterial and Anti Platelet Activity of Ethanolic Leaf Extract of Physalis angulata. Research J. Pharmacognosy and Phytochemistry 2010; 2(1): 67-69.
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