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Research Journal of Pharmacognosy and Phytochemistry
ISSN: 0975-4385(Online), 0975-2331(Print)
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Evaluation of Wound Healing Potential of Ethanolic Extracts of Various Parts of Phyllanthus simplex Retz.
Arasan Elayaraja1*, M Vijayalakshmi2 and Devalarao Garikapati1
1KVSR Siddhartha College of Pharmaceutical Sciences, Vijayawada- 520 010, Andhra Pradesh, India.
2Department of Microbiology, Acharya Nagarjuna University, Acharyanagar, Guntur, Andhra Pradesh, India.
Wound healing is a complex dynamic process that results in the restoration of anatomic continuity and function. The present study has proved that the wound healing potential of ethanolic extract obtained from roots of Phyllanthus simplex Retz showed a significant effect than the same extract obtained from other parts of the plant. That extract showed a facilitatory epithelisation and wound contraction than other parts extracts. The root extract animal groups showed a high collagen content than other extracts and the control groups. Hexosamine content and ascorbic acid levels showed an increased level of the extract. Ascorbic acid is reported to have scavenging activity and inhibition of lipid peroxidation, which helps to show a better healing effect for the test groups.
Wound healing, Collagen, Hydroxy proline, Hexose amine, Epithelization.
Arasan Elayaraja, M Vijayalakshmi, Devalarao Garikapati. Evaluation of Wound Healing Potential of Ethanolic Extracts of Various Parts of Phyllanthus simplex Retz. Research J. Pharmacognosy and Phytochemistry 2010; 2(1): 34-36.
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