Author(s): Vijay R Salunkhe, Satish B Bhise

Email(s): vrsalunkhe@rediffmail.com

DOI: Not Available

Address: Vijay R Salunkhe and Satish B Bhise
Govt. College of Pharmacy, Vidyanagar, Tal. Karad- 415 124, Dist. Satara, M. S. India.
*Corresponding Author

Published In:   Volume - 1,      Issue - 3,     Year - 2009


ABSTRACT:
Objective: To study the effect of dried powder of leaves of S rebaudiana on antidiabetic potential of developed Madhujeevan churna by using alloxan treated Wistar rats. Materials and Methods: Madhujeevan churna was formulated and developed using Aegle marmelos, Curcuma longa, Azadichta indica, Momordica charantia, Gymnema sylvestre, Salacia reticulata, and Emblica officinalis as active ingredients and Stevia rebaudiana as natural sweetener and nutraceuticals. Churna without Stevia (bitter Churna) and Madhujeevan churna with Stevia (sweet Churna) were evaluated for its antidiabetic activity in alloxan induced diabetic rats. Bitter and sweet Churnas were tested for their antidiabetic potential by blood sugar level, average animal weight and applicable biochemical parameters. Glibenclamide was used as a standard. Results: Both Churnas showed antidiabetic potential in comparison with standard Glibenclamide. Both Churnas were significantly superior to control in reducing blood sugar as well as weight of animals. Madhujeevan Churna containing natural sweetener showed marked reduction in total cholesterol, HDL cholesterol, tiglyceride, SGOT, SGPT, VLDL, creatinine and uric acid as compare to standard and bitter Madhujeevan churna. Conclusion: Sweet churna showed significant synergistic effect in comparison to Churna without Stevia. Aqueous extract of dried leaves of Stevia rebaudiana acts as a natural antidiabetic agent.


Cite this article:
Vijay R Salunkhe , Satish B Bhise. Synergistic Effect of Natural Sweetener on Antidiabetic Potential of Madhujeevan churna. Research J. Pharmacognosy and Phytochemistry 2009; 1(3): 204-208.


Recomonded Articles:

Author(s): S. Mohan Raj*, Shahid Mohammed, Vinoth Kumar S, Santhosh Kumar C, Subal Debnath

DOI:         Access: Open Access Read More

Author(s): Kavitha PG, M Umadevi

DOI: 10.5958/0975-4385.2016.00009.1         Access: Open Access Read More

Author(s): Sanjib Bahadur, Amit Roy, Ranabir Chanda, Pragya Baghel, Suman Saha, Ananta Choudhury

DOI: 10.5958/0975-4385.2016.00030.3         Access: Open Access Read More

Author(s): L. Kavitha, B. Kumaravel, G. Sriram Prasath, S. Subramanian

DOI:         Access: Open Access Read More

Author(s): Shubhashree M N, Venkateshwarlu G, Doddamani S H

DOI:         Access: Open Access Read More

Author(s): Dongare SS, Maske AP, Patil SM, Umbare RP ,Mate GS

DOI:         Access: Open Access Read More

Author(s): Ena Gupta, Abubakar Mohammed, Shalini Purwar, Syed Ibrahim Rizvi, Shanthy Sundaram

DOI: 10.5958/0975-4385.2017.00030.9         Access: Open Access Read More

Author(s): U. T. Karimov, Zhao Hai Qing, H.A. Aisa

DOI: 10.5958/0975-4385.2018.00035.3         Access: Open Access Read More

Author(s): Preeti Tiwari, Rakesh K. Patel, T.S. Eashwari

DOI:         Access: Open Access Read More

Author(s): Vijay R Salunkhe , Satish B Bhise

DOI:         Access: Open Access Read More

Author(s): Murugan M, Uma Maheswara Reddy C, Vedhapal Jeyamani S, Babu Ananth D, Umasankar K

DOI:         Access: Open Access Read More

Author(s): Arora Dhiraj, KL Senthilkumar, L Samuel Joshua, K Senthilkumar , T Karthiyayini,

DOI:         Access: Open Access Read More

Author(s): RB Goswami, Neelima Goswami, P Khare, S Choudhary, AK Pathak

DOI:         Access: Open Access Read More

Author(s): Anita S Wanjari, Priti R Desai

DOI: 10.5958/0975-4385.2015.00023.0         Access: Open Access Read More

Author(s): T Pandu Raju, KJR Shastri , C Srinivas Reddy, VM Reddy

DOI:         Access: Open Access Read More

Author(s): V. Ravichandiran ,Sankaradoss Nirmala

DOI:         Access: Open Access Read More

Author(s): Sneha Anarthe, Sanjay Chaudhari

DOI:         Access: Open Access Read More

Author(s): Benito Johnson, Roja rani. A, P. Ajay Kumar, Nehru Sai Suresh Chalichem, Ashokkumar Javvadi.

DOI:         Access: Open Access Read More

Author(s): Dongare SS, Maske AP, Patil SM, Umbare RP , Mate GS

DOI:         Access: Open Access Read More

Research Journal of Pharmacognosy and Phytochemistry (RJPP) is an international, peer-reviewed journal, devoted to pharmacognosy...... Read more >>>

RNI: Not Available                     
DOI: 10.5958/0975-4385 


Recent Articles




Tags