List of Refereed Journals published by UGC, New Delhi on 11-01-2017-- Research Journal of Pharmacy and Technology (Sr. No.-275); Asian Journal of Management (Sr. No.-3986); Asian Journal of Research in Chemistry (Sr. No.-4008); Research Journal of Engineering and Technology (Sr. No.-31787); Researc (22-Jan-2017)        |

Volume No. :   1

Issue No. :  3

Year :  2009

ISSN Print :  0975-2331

ISSN Online :  0975-4385


Registration

Allready Registrered
Click to Login

Antiulcer Activity of 50% Hydroethanolic Leaf Extract of Ruellia tuberosa l. and Dipteracanthus patulus (Jaca) On Pylorus Ligated Gastric Ulcer Model



Address:   A Manikandan and D Victor Arokia Doss*
Department of Biochemistry, PSG College of Arts and Science, Coimbatore, Tamil Nadu, India.
*Corresponding Author
DOI No:

ABSTRACT:
The antiulcer activity of 50% hydroethanolic leaf extract of Ruellia tuberose L. and Dipteracanthus patulus (Jaca) was evaluated in rats against pylorus ligated gastric ulcer model. The plant extract were administered orally at a dose of 500mg/kg and famotidine at the dose of 20 mg/kg (standard drug). Ulcer index was common parameter studied in the ulcer model, further the gastric pH, total and free acidity, gastric volume and antioxidant leaves such as SOD, CAT, GSH and the effect on LPO and protein were analysed. Both the extracts produced significant reduction in ulcer index, along with increase in the antioxidant enzyme and protein leaves as compared to control group and the lipid peroxidation was reduced in the treated and drug administered groups. Thus the plant extracts possess, significant antiulcer as well as antioxidant property.
KEYWORDS:
Antiulcer, antioxidant, ulcer index, Ruellia tuberose .L, Dipteracanthus patulus
Cite:
A Manikandan, D Victor Arokia Doss. Antiulcer Activity of 50% Hydroethanolic Leaf Extract of Ruellia tuberosa l. and Dipteracanthus patulus (Jaca) On Pylorus Ligated Gastric Ulcer Model. Research J. Pharmacognosy and Phytochemistry 2009; 1(3): 198-200.
[View HTML]      [View PDF]



Visitor's No. :   49711